Evidence map›Paper›PMID 36738374›Full record

ArticleNeurotoxicity research2023

Rutin Attenuates Oxidative Stress Via PHB2-Mediated Mitophagy in MPP

Xiaoyi Lai, Yongjiang Zhang, Jiannan Wu, Mengmeng Shen, Shiyi Yin, Junqiang Yan

Abstract read
PubMed Publisher
In one paragraph

Article in Neurotoxicity research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
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  12. PHB2 Alleviates Neurotoxicity of Prion Peptide PrPInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaoyi LaiNeuromolecular Biology Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Jinghua Road 24, Luoyang, 471003, People's Republic of China.
Yongjiang ZhangNeuromolecular Biology Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Jinghua Road 24, Luoyang, 471003, People's Republic of China.
Jiannan WuNeuromolecular Biology Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Jinghua Road 24, Luoyang, 471003, People's Republic of China.
Mengmeng ShenNeuromolecular Biology Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Jinghua Road 24, Luoyang, 471003, People's Republic of China.
Shiyi YinNeuromolecular Biology Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Jinghua Road 24, Luoyang, 471003, People's Republic of China.
Junqiang YanNeuromolecular Biology Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Jinghua Road 24, Luoyang, 471003, People's Republic of China. yanjq@haust.edu.cn.
First Affiliated Hospital of Henan University of Science and Technology · CN

Funding

Henan Medical Science and Technology Research Program Joint Construction Project LHGJ20200566Henan Medical Science and Technology Research Program Joint Construction Project LHGJ20200567Henan Medical Science and Technology Research Program Joint Construction Project LHGJ20210593Henan Medical Science and Technology Research Program province-ministry co-sponsorship SBGJ202002099the Key Science and Technology Research of Henan Province 222102310351 and 212102310216
6 · The paper itself

Abstract

Oxidative stress plays a crucial role in the occurrence and development of Parkinson's disease (PD). Rutin, a natural botanical ingredient, has been shown to have antioxidant properties. Therefore, the aim of this study was to investigate the neuroprotective effects of rutin on PD and the underlying mechanisms. MPP

Indexed as

NeuroblastomaParkinson Disease1-Methyl-4-phenylpyridiniumAntioxidantsApoptosisCell Line, TumorHumansMicrotubule-Associated ProteinsMitophagyNF-E2-Related Factor 2Oxidative StressReactive Oxygen SpeciesRutin1-Methyl-4-phenylpyridiniumAntioxidantsMicrotubule-Associated ProteinsNF-E2-Related Factor 2Reactive Oxygen SpeciesRutinMitophagyMPP+Oxidative stressPHB2Rutin

Identifiers

PMID36738374
OpenAlexW4319216483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.