Evidence map›Paper›PMID 36738244›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2023

Catheter ablation improved ejection fraction in persistent AF patients: a DECAAF-II sub analysis.

Mario Mekhael, Botao Shan, Charbel Noujaim, Nour Chouman, Alaa Assaf, Hadi Younes, Abdel Hadi El Hajjar, Lilas Dagher, Han Feng, Hua He and 9 more

Open access · hybridAbstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Sex-specific outcomes and left atrial remodeling following catheter ablation of persistent atrial fibrillation: results from the DECAAF II trial.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Sex differences in atrial fibrillation ablation outcomes in patients with heart failure.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Mario MekhaelTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0001-8809-5419
Botao ShanTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0003-2219-0709
Charbel NoujaimTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0002-3179-4398
Nour ChoumanTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0002-6624-1590
Alaa AssafTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0001-6443-798X
Hadi YounesTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0002-7202-1164
Abdel Hadi El HajjarTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0003-4820-8102
Lilas DagherTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.
Han FengTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0003-3163-8931
Hua HeTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0001-8989-0297
Cong ZhaoTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.
Omar KreidiehTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0001-6189-2821
Chan Ho LimTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0001-9998-5601
Chao HuangTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0002-8961-7976
Tarek AyoubTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0003-2128-1051
Eugene KholmovskiDepartment of Biomedical Engineering, Johns Hopkins University, 733 N Broadway, Baltimore, MD 21205, USA.ORCID 0000-0002-3271-7247
Mihail CheluBaylor St. Luke's Medical Center, 1101 Bates Ave, Houston, TX 77030, USA.ORCID 0000-0001-9688-1604
Nassir MarroucheTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0003-0454-0541
Eoin DonnellanTulane Research and Innovation for Arrhythmia Discoveries- TRIAD Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.ORCID 0000-0002-2878-9061
Tulane University · USJohns Hopkins University · USSt. Luke's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aim of our study was to assess differences in post-ablation atrial fibrillation (AF) recurrence and burden and to quantify the change in LVEF across different congestive heart failure (CHF) subcategories of the DECAAF-II population. METHODS AND

resultsDifferences in the primary outcome of AF recurrence between CHF and non-CHF groups was calculated. The same analysis was performed for the three subgroups of CHF and the non-CHF group. Differences in AF burden after the 3-month blanking period between CHF and non-CHF groups was calculated. Improvement in LVEF was calculated and compared across the three CHF groups. Improvement was also calculated across different fibrosis stages. There was no significant differences in AF recurrence and AF burden after catheter ablation between CHF and non-CHF patients and between different CHF subcategories. Patients with heart failure with reduced ejection fraction (HFrEF) experienced the greatest improvement in EF following catheter ablation (CA, 16.66% ± 11.98, P < 0.001) compared to heart failure with moderately reduced LVEF, and heart failure with preserved EF (10.74% ± 8.34 and 2.00 ± 8.34 respectively, P-value < 0.001). Moreover, improvement in LVEF was independent of the four stages of atrial fibrosis (7.71 vs. 9.53 vs. 5.72 vs. 15.88, from Stage I to Stage IV respectively, P = 0.115).

conclusionAtrial fibrillation burden and recurrence after CA is similar between non-CHF and CHF patients, independent of the type of CHF. Of all CHF groups, those with HFrEF had the largest improvement in LVEF after CA. Moreover, the improvement in ventricular function seems to be independent of atrial fibrosis in patients with persistent AF.

Indexed as

Atrial FibrillationCatheter AblationHeart FailureVentricular Dysfunction, LeftFibrosisHumansStroke VolumeTreatment OutcomeVentricular Function, LeftAtrial FibrillationCatheter AblationCongestive Heart FailureEjection Fraction

Identifiers

PMID36738244
PMCPMC10062294
OpenAlexW4319164443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.