Evidence map›Paper›PMID 36737759›Full record

ArticleJournal of translational medicine2023

Identification and validation of a novel survival prediction model based on the T-cell phenotype in the tumor immune microenvironment and peripheral blood for gastric cancer prognosis.

Jing Ma, Jianhui Li, Nan He, Meirui Qian, Yuanyuan Lu, Xin Wang, Kaichun Wu

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Immune Marker Spatial Distribution and Clinical Outcome after PD-1 Blockade in Mismatch Repair-deficient, Advanced Colorectal Carcinomas.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jing Ma *Department of Gastroenterology, Tangdu Hospital, The Air Force Military Medical University, Xi'an, 710032, Shaanxi, China. majing1128fmmu@163.com.ORCID 0000-0003-4147-4619
Jianhui Li *Department of Infectious Diseases, Tangdu Hospital, The Air Force Military Medical University, Xi'an, China.
Nan HeState Key Laboratory of Cancer Biology and Institute of Digestive Diseases, The Air Force Military Medical University, Xi'an, China.
Meirui QianNational Translational Science Center for Molecular Medicine, The Air Force Military Medical University, Xi'an, China.
Yuanyuan LuState Key Laboratory of Cancer Biology and Institute of Digestive Diseases, The Air Force Military Medical University, Xi'an, China.
Xin WangDepartment of Gastroenterology, Tangdu Hospital, The Air Force Military Medical University, Xi'an, 710032, Shaanxi, China.
Kaichun WuState Key Laboratory of Cancer Biology and Institute of Digestive Diseases, The Air Force Military Medical University, Xi'an, China. kaicwu@fmmu.edu.cn.
Tang Du Hospital · CNState Key Laboratory of Cancer BiologyAir Force Engineering University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe correlation and difference in T-cell phenotypes between peripheral blood lymphocytes (PBLs) and the tumor immune microenvironment (TIME) in patients with gastric cancer (GC) is not clear. We aimed to characterize the phenotypes of CD8

methodsMultiplex immunofluorescence staining and flow cytometry were used to detect the expression of inhibitory molecules (IMs) and active markers (AMs) in CD8

resultsThe percentage of PD-1

conclusionWe established a comprehensive and robust survival prediction model based on the T-cell phenotype in the TIME and PBLs for GC prognosis.

Indexed as

CD8-Positive T-LymphocytesStomach NeoplasmsB7-H1 AntigenHepatitis A Virus Cellular Receptor 2HumansLymphocytes, Tumor-InfiltratingPrognosisProgrammed Cell Death 1 ReceptorTumor MicroenvironmentB7-H1 AntigenHepatitis A Virus Cellular Receptor 2Programmed Cell Death 1 ReceptorGastric cancerInhibitory moleculePeripheral blood lymphocytesSurvival prediction modelTumor immune microenvironment

Identifiers

PMID36737759
PMCPMC9896795
OpenAlexW4319081324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.