ArticleBMC pulmonary medicine2023
Clinical characteristics of airway impairment assessed by impulse oscillometry in patients with chronic obstructive pulmonary disease: findings from the ECOPD study in China.
Article in BMC pulmonary medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07185581 (Evaluation of Small Airway Function During COPD Exacerbation and Recovery Using Impulse Oscillometry), which is not on this map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Small Airway Function During COPD Exacerbation and Recovery Using Impulse Oscillometry (IOS) Device
Who cites it
19 citing papers in PubMed.
- Association of childhood growth with adult lung function: A prospective urban birth cohort study from India.The Indian journal of medical research · 2026Article
- Mortality among people with airflow limitation according to the fixed ratio criterion but not the lower limit of normal criterion.Journal of thoracic disease · 2026Article
- Long-term variability of impulse oscillometry defined small airway dysfunction in participants with and without chronic obstructive pulmonary disease.BMJ open respiratory research · 2026Article
- Small Airway Dysfunction in Chronic Obstructive Pulmonary Disease Pathology: Assessment and Clinical Implications.Tuberculosis and respiratory diseases · 2026Article
- Respiratory mechanics: modelling, measurement and clinical applications-a review.Biomedical engineering online · 2026Review
- Impulse oscillometry and traditional pulmonary function testing: correlation, advances and clinical implications.BMJ open respiratory research · 2026Review
- A case report on nebulized human umbilical cord mesenchymal stem cell-derived exosome therapy for asthma and chronic obstructive pulmonary disease: A preliminary clinical evaluation.SAGE open medical case reports · 2026Article
- Impulse oscillometry-defined airway abnormalities as a treatable trait for mild-to-moderate COPD: a prospective cohort study with 3-year follow-up.ERJ open research · 2025Article
- Oscillometry findings in altered spirometry patterns and relationship to respiratory symptoms.ERJ open research · 2025Article
- The intra-breath changes of reactance at low frequency in impulse oscillometry: differentiating obstructive airway disease and Interstitial Lung Disease.BMC pulmonary medicine · 2025Article
- Peripheral airway function and disease burden in COPD.ERJ open research · 2025Article
- Role of impulse oscillometry in chronic obstructive pulmonary disease and asthma-chronic obstructive pulmonary disease overlap.Clinical and translational allergy · 2025Article
- Association between impaired diffusion capacity and small airway dysfunction: a cross-sectional study.ERJ open research · 2025Article
- Risk Factors for Acute Exacerbation in Patients with COPD Group E in Ningbo: Risk Analysis of Irregular Review, Cardiovascular Complications, and Lung Function Decline.International journal of chronic obstructive pulmonary disease · 2025Article
- Diagnosis and evaluation of small airway disease and COPD using impulse oscillometry.Scientific reports · 2024Article
- Oscillometry-Defined Small Airway Dysfunction in Patients with Chronic Obstructive Pulmonary Disease.Tuberculosis and respiratory diseases · 2024Article
- Clinical characterization and outcomes of impulse oscillometry-defined bronchodilator response: an ECOPD cohort-based study.Respiratory research · 2024Observational
- Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients.Journal of medicine and life · 2023Article
- Oscillometry in Lung Function Assessment: A Comprehensive Review of Current Insights and Challenges.Cureus · 2023Review
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
backgroundThe role of airway impairment assessed by impulse oscillometry (IOS) in patients with chronic obstructive pulmonary disease (COPD) remains unclear. Therefore, this study aimed to analyze the proportion and clinical characteristics of airway impairment assessed by IOS across COPD severities, and explore whether airway impairment is a subtype of COPD.
methodsThis study was based on cross-sectional data from the ECOPD cohort in Guangdong, China. Subjects were consecutively recruited from July 2019 to August 2021. They filled out questionnaires and underwent lung function tests, IOS and computed tomography (CT). COPD was defined as post-bronchodilator forced expiratory volume in one second/forced vital capacity < lower limit of normal (LLN). Meanwhile, airway impairment was defined as IOS parameters > upper limit of normal or < LLN. On the one hand, Poisson regression was employed to analyze the associations between acute exacerbations of COPD (AECOPD) in the previous year and airway impairment. On the other hand, logistic regression was used to assess differences in CT imaging between patients with IOS parameters' abnormalities and patients with normal IOS parameters.
results768 COPD subjects were finally enrolled in the study. The proportion of airway impairment assessed by R
conclusionsAirway impairment assessed by IOS may be a subtype of COPD. Future studies are warranted to identify the underlying mechanisms and longitudinal progression of airway impairment.
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