Evidence map›Paper›PMID 36737659›Full record

ReviewBritish journal of cancer2023

Proactive breast cancer risk assessment in primary care: a review based on the principles of screening.

Juliet A Usher-Smith, Sarah Hindmarch, David P French, Marc Tischkowitz, Sowmiya Moorthie, Fiona M Walter, Rebecca A Dennison, Francisca Stutzin Donoso, Stephanie Archer, Lily Taylor and 4 more

Open access · hybridAbstract readReview
In one paragraph

Review in British journal of cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  14. Risk-Stratified Breast Cancer Screening in Malaysia: Challenges and Opportunities.Asian Pacific journal of cancer prevention : APJCP · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Implementation of risk assessment process for breast cancer risk in primary care.Journal of cancer prevention & current research · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Juliet A Usher-SmithThe Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. jau20@medschl.cam.ac.uk.ORCID 0000-0002-8501-2531
Sarah HindmarchManchester Centre for Health Psychology, Division of Psychology and Mental Health, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-9549-1177
David P FrenchManchester Centre for Health Psychology, Division of Psychology and Mental Health, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-7663-7804
Marc TischkowitzDepartment of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK.
Sowmiya MoorthiePHG Foundation, University of Cambridge, Cambridge, UK.ORCID 0000-0002-7790-2630
Fiona M WalterThe Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Rebecca A DennisonThe Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.ORCID 0000-0002-0847-0723
Francisca Stutzin DonosoThe Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Stephanie ArcherThe Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Lily TaylorThe Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.ORCID 0000-0002-0832-9244
Jon EmeryCentre for Cancer Research and Department of General Practice, University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0002-5274-6336
Stephen MorrisThe Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.ORCID 0000-0002-5828-3563
Douglas F EastonCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Antonis C AntoniouCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
University of Cambridge · GBManchester Academic Health Science Centre · GBQueen Mary University of London · GBThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the UK, the National Institute for Health and Care Excellence (NICE) recommends that women at moderate or high risk of breast cancer be offered risk-reducing medication and enhanced breast screening/surveillance. In June 2022, NICE withdrew a statement recommending assessment of risk in primary care only when women present with concerns. This shift to the proactive assessment of risk substantially changes the role of primary care, in effect paving the way for a primary care-based screening programme to identify those at moderate or high risk of breast cancer. In this article, we review the literature surrounding proactive breast cancer risk assessment within primary care against the consolidated framework for screening. We find that risk assessment for women under 50 years currently satisfies many of the standard principles for screening. Most notably, there are large numbers of women at moderate or high risk currently unidentified, risk models exist that can identify those women with reasonable accuracy, and management options offer the opportunity to reduce breast cancer incidence and mortality in that group. However, there remain a number of uncertainties and research gaps, particularly around the programme/system requirements, that need to be addressed before these benefits can be realised.

Indexed as

Breast NeoplasmsBreastEarly Detection of CancerFemaleHumansPrimary Health CareRisk Assessment

Identifiers

PMID36737659
PMCPMC9897164
OpenAlexW4319080437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.