Evidence map›Paper›PMID 36737644›Full record

ArticleNPJ digital medicine2023

Towards precision medicine based on a continuous deep learning optimization and ensemble approach.

Jian Li, Linyuan Jin, Zhiyuan Wang, Qinghai Peng, Yueai Wang, Jia Luo, Jiawei Zhou, Yingying Cao, Yanfen Zhang, Min Zhang and 16 more

Open access · goldAbstract read
In one paragraph

Article in NPJ digital medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 6 institutions in 2 countries.

Jian LiDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China. 707779628@qq.com.ORCID http://orcid.org/0000-0001-9392-9449
Linyuan Jin *Department of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Zhiyuan WangDepartment of Ultrasound, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, China. wangzhiyuan@hnca.org.cn.ORCID http://orcid.org/0000-0002-6867-2386
Qinghai PengDepartment of Ultrasound, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China. pqh12079@aliyun.com.ORCID http://orcid.org/0000-0002-5726-3202
Yueai WangDepartment of Ultrasound, The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Changsha, Hunan, China. 497375291@qq.com.ORCID http://orcid.org/0000-0003-1624-9276
Jia Luo *Department of Ultrasound, The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Changsha, Hunan, China.
Jiawei Zhou *Department of Ultrasound, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Yingying Cao *Department of Ultrasound, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, China.
Yanfen ZhangDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Min ZhangDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Yuewen QiuDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Qiang HuDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Liyun ChenDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Xiaoyu YuDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Xiaohui ZhouDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Qiong LiDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Shu ZhouDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Si HuangDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Dan LuoDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Xingxing MaoDepartment of Ultrasound, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
Yi YuDepartment of Ultrasound, The People's Hospital of Liuyang, Liuyang, Hunan, China.
Xiaomeng YangDepartment of Ultrasound, Huaihua First People's Hospital, Huaihua, Hunan, China.
Chiling PaneBay Inc., San Jose, CA, USA.
Hongxin LiGuangzhou Yirui Zhiying Technology Co. Ltd., Guangzhou, Guangdong, China.
Jingchao WangGuangzhou Yirui Zhiying Technology Co. Ltd., Guangzhou, Guangdong, China.
Jieke LiaoGuangzhou Yirui Zhiying Technology Co. Ltd., Guangzhou, Guangdong, China.
Changsha Central Hospital · CNCentral South University · CNFirst Affiliated Hospital of Hunan University of Traditional Chinese Medicine · CNeBay (United States) · USHuaian First People’s Hospital · CNLiuyang City Maternal and Child Health Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed a continuous learning system (CLS) based on deep learning and optimization and ensemble approach, and conducted a retrospective data simulated prospective study using ultrasound images of breast masses for precise diagnoses. We extracted 629 breast masses and 2235 images from 561 cases in the institution to train the model in six stages to diagnose benign and malignant tumors, pathological types, and diseases. We randomly selected 180 out of 3098 cases from two external institutions. The CLS was tested with seven independent datasets and compared with 21 physicians, and the system's diagnostic ability exceeded 20 physicians by training stage six. The optimal integrated method we developed is expected accurately diagnose breast masses. This method can also be extended to the intelligent diagnosis of masses in other organs. Overall, our findings have potential value in further promoting the application of AI diagnosis in precision medicine.

Identifiers

PMID36737644
PMCPMC9898519
OpenAlexW4319080312

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.