ArticleNature communications2023
Macromolecular sheets direct the morphology and orientation of plate-like biogenic guanine crystals.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Extreme Biomimetics: Achievements and Fundamental Challenges for the Future.Biomimetics (Basel, Switzerland) · 2026Review
- Damselflies overcome color saturation barriers of photonic glasses via pigment loading and refractive index modulation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Control Strategies in Guanine Biocrystallization.Angewandte Chemie (International ed. in English) · 2026Review
- Lysosome-related organelles orchestrate guanine crystal formation in pigment cells.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Spatial Relations between Coccoliths and Their Confining Membrane During Crystal Morphogenesis.Journal of the American Chemical Society · 2026Article
- The Molecular Basis of Growth Control in Guanine Crystals.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Acid enables biogenic crystallization.Nature chemical biology · 2026Article
- pH variations enable guanine crystal formation within iridosomes.Nature chemical biology · 2026Article
- Crystalline guanine: Rediscovery of a long-overlooked structure of unicellular eukaryotes.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Purine Molecular Interactions Determine Anisotropic Shape of Zebrafish Biogenic Crystals.Small methods · 2025Article
- Guanine Crystal Formation at Physiological pH.Crystal growth & design · 2025Article
- Guanine Crystallization by Particle Attachment.Journal of the American Chemical Society · 2025Article
- Specialized molecular pathways drive the formation of light-scattering assemblies in leucophores.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genetic control over biogenic crystal morphogenesis in zebrafish.Nature chemical biology · 2025Article
- Guanine crystal formation by the unicellular organism Phacotus lenticularis is part of a cellular stress response.PloS one · 2025Article
- Rationalizing the Influence of Small-Molecule Dopants on Guanine Crystal Morphology.Chemistry of materials : a publication of the American Chemical Society · 2024Article
- The rise and fall of adenine clusters in the gas phase: a glimpse into crystal growth and nucleation.Analytical and bioanalytical chemistry · 2024Article
- Structure Determination of Biogenic Crystals Directly from 3D Electron Diffraction Data.Crystal growth & design · 2024Article
- Intermediate filaments spatially organize intracellular nanostructures to produce the bright structural blue of ribbontail stingrays across ontogeny.Frontiers in cell and developmental biology · 2024Article
- Biomineralization and Properties of Guanine Crystals.Molecules (Basel, Switzerland) · 2023Review
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals precisely control the morphology and assembly of guanine crystals to produce diverse optical phenomena in coloration and vision. However, little is known about how organisms regulate crystallization to produce optically useful morphologies which express highly reflective crystal faces. Guanine crystals form inside iridosome vesicles within chromatophore cells called iridophores. By following iridosome formation in developing scallop eyes, we show that pre-assembled, fibrillar sheets provide an interface for nucleation and direct the orientation of the guanine crystals. The macromolecular sheets cap the (100) faces of immature guanine crystals, inhibiting growth along the π-stacking growth direction. Crystal growth then occurs preferentially along the sheets to generate highly reflective plates. Despite their different physical properties, the morphogenesis of iridosomes bears a striking resemblance to melanosome morphogenesis in vertebrates, where amyloid sheets template melanin deposition. The common control mechanisms for melanin and guanine formation inspire new approaches for manipulating the morphologies and properties of molecular materials.
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