Evidence map›Paper›PMID 36737102›Full record

ArticleRNA (New York, N.Y.)2023

Transcriptome-wide analyses of piRNA binding sites suggest distinct mechanisms regulate piRNA binding and silencing in

Wei-Sheng Wu, Jordan S Brown, Sheng-Cian Shiue, Chi-Jung Chung, Dong-En Lee, Donglei Zhang, Heng-Chi Lee

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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  6. Analysis of crosslinking sites suggestsbioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Wei-Sheng Wu *Department of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Jordan S Brown *Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois 60637, USA.
Sheng-Cian ShiueDepartment of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Chi-Jung ChungDepartment of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Dong-En LeeDepartment of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Donglei ZhangDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois 60637, USA.ORCID 0000-0002-2720-1414
Heng-Chi LeeDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois 60637, USA hengchilee@uchicago.edu.ORCID 0000-0001-8154-906X
National Cheng Kung University · TWUniversity of Chicago · US

Funding

PREDOCTORAL TRAINING IN GENETICS AND REGULATIONT32GM007197 · NIGMS · UNIVERSITY OF CHICAGO · PI ROTHMAN-DENES, LUCIA B. B · 1985 to 2020
$17.0M
piRNA-mediated genome surveillance of germline transcriptsR01GM132457 · NIGMS · UNIVERSITY OF CHICAGO · PI LEE, HENG-CHI · 2019 to 2023
$1.7M
NIGMS NIH HHS R01 GM132457NIGMS NIH HHS T32 GM007197
6 · The paper itself

Abstract

PIWI-interacting RNAs (piRNAs) protect genome integrity by silencing transposon mRNAs and some endogenous mRNAs in various animals. However,

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsArgonaute ProteinsBinding SitesPiwi-Interacting RNARNA, Double-StrandedRNA, Small InterferingTranscriptomeArgonaute ProteinsCaenorhabditis elegans ProteinsCSR-1 protein, C elegansPiwi-Interacting RNARNA, Double-StrandedRNA, Small InterferingArgonautegene regulationgene silencingpiRNAPIWItranscriptome surveillance

Identifiers

PMID36737102
PMCPMC10158993
OpenAlexW4319072292

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.