Evidence map›Paper›PMID 36737089›Full record

SynthesisBMJ open2023

Impact of minimum unit pricing on alcohol-related hospital outcomes: systematic review.

Tobias Maharaj, Colin Angus, Niamh Fitzgerald, Kathryn Allen, Stephen Stewart, Siobhan MacHale, John D Ryan

Erratum issuedAbstract readSystematic Review
In one paragraph

Synthesis in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Public health policies to prevent alcohol-related liver disease.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Tobias MaharajRoyal College of Surgeons in Ireland, Dublin, Ireland.ORCID 0000-0002-6600-4982
Colin AngusSheffield Alcohol Research Group, School of Health and Related Research, University of Sheffield, Sheffield, UK.ORCID 0000-0003-0529-4135
Niamh FitzgeraldInstitute for Social Marketing, UK Centre for Tobacco and Alcohol Studies, School of Health Sciences, University of Stirling, Stirling, UK.ORCID 0000-0002-3643-8165
Kathryn AllenHepatology Unit, Beaumont Hospital, Dublin, Ireland.
Stephen StewartCentre for Liver Disease, Mater Misericordiae University Hospital, Dublin, Ireland.
Siobhan MacHaleRoyal College of Surgeons in Ireland, Dublin, Ireland.
John D RyanRoyal College of Surgeons in Ireland, Dublin, Ireland johnryan2@beaumont.ie.ORCID 0000-0002-2805-8808

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the impact of minimum unit pricing (MUP) on the primary outcome of alcohol-related hospitalisation, and secondary outcomes of length of stay, hospital mortality and alcohol-related liver disease in hospital.

designDatabases MEDLINE, Embase, Scopus, APA Psycinfo, CINAHL Plus and Cochrane Reviews were searched from 1 January 2011 to 11 November 2022. Inclusion criteria were studies evaluating the impact of minimum pricing policies, and we excluded non-minimum pricing policies or studies without alcohol-related hospital outcomes. The Effective Public Health Practice Project tool was used to assess risk of bias, and the Bradford Hill Criteria were used to infer causality for outcome measures.

settingMUP sets a legally required floor price per unit of alcohol and is estimated to reduce alcohol-attributable healthcare burden. PARTICIPANT: All studies meeting inclusion criteria from any country

interventionMinimum pricing policy of alcohol PRIMARY AND SECONDARY OUTCOME MEASURES:

results22 studies met inclusion criteria; 6 natural experiments and 16 modelling studies. Countries included Australia, Canada, England, Northern Ireland, Ireland, Scotland, South Africa and Wales. Modelling studies estimated that MUP could reduce alcohol-related admissions by 3%-10% annually and the majority of real-world studies demonstrated that acute alcohol-related admissions responded immediately and reduced by 2%-9%, and chronic alcohol-related admissions lagged by 2-3 years and reduced by 4%-9% annually. Minimum pricing could target the heaviest consumers from the most deprived groups who tend to be at greatest risk of alcohol harms, and in so doing has the potential to reduce health inequalities. Using the Bradford Hill Criteria, we inferred a 'moderate-to-strong' causal link that MUP could reduce alcohol-related hospitalisation.

conclusionsNatural studies were consistent with minimum pricing modelling studies and showed that this policy could reduce alcohol-related hospitalisation and health inequalities. PROSPERO REGISTRATION NUMBER: CRD42021274023.

Indexed as

Alcoholic BeveragesEthanolAlcohol DrinkingCommerceCosts and Cost AnalysisHospitalsHumansPolicyEthanolAdult intensive & critical careHealth policyHepatologyPUBLIC HEALTHSubstance misuse

Identifiers

PMID36737089
PMCPMC9900069

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.