Evidence map›Paper›PMID 36737085›Full record

ArticleBMJ open2023

Association of sarcopenia with liver fibrosis and steatohepatitis in non-alcoholic fatty liver disease: protocol for a systematic review and meta-analysis.

Zheng Wang, Saixin Li, Kenan Wang, Min Zhang, Jie Wu, Dongbin Liu, Kuo Liang

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zheng WangDepartment of General Surgery, Xuanwu Hospital Capital Medical University, Beijing, China.ORCID 0000-0001-6262-2102
Saixin LiDepartment of General Surgery, Xuanwu Hospital Capital Medical University, Beijing, China.
Kenan WangDepartment of General Surgery, Xuanwu Hospital Capital Medical University, Beijing, China.
Min ZhangDepartment of Anesthesiology, Xuanwu Hospital Capital Medical University, Beijing, China.
Jie WuDepartment of Anesthesiology, Xuanwu Hospital Capital Medical University, Beijing, China.
Dongbin LiuDepartment of General Surgery, Xuanwu Hospital Capital Medical University, Beijing, China.
Kuo LiangDepartment of General Surgery, Xuanwu Hospital Capital Medical University, Beijing, China liangkuo611@xwh.ccmu.edu.cn.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNon-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disorder over the last four decades, more evidence shows a high prevalence of sarcopenia in NAFLD that may influence disease severity. This meta-analysis aims to determine the association of sarcopenia with liver fibrosis and steatohepatitis in NAFLD. METHODS AND ANALYSIS: We will conduct the literature search using Medline (via PubMed), Web of Science databases, EMBASE, Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Reviews (from the date of inception to 1 May 2022). There will be no restriction to the publication year. Two reviewers will independently screen the articles and abstract key study characteristics. The outcome of this meta-analysis is the strength of association of sarcopenia with liver fibrosis and steatohepatitis in NAFLD. The STATA (V.14, StataCorp, 2015) will be used to carry out the statistical analysis. Comprehensive evaluation of bias risk and heterogeneity will be performed before data synthesis. Also, consistency and evidence quality will be assessed. ETHICS AND DISSEMINATION: There will be no need of ethics approval as this systematic review is summary and analysis of existing literature. Final results may be presented in international conferences or a peer-reviewed journal. PROSPERO REGISTRATION NUMBER: CRD42022322685.

Indexed as

Non-alcoholic Fatty Liver DiseaseSarcopeniaHumansLiver CirrhosisMeta-Analysis as TopicResearch DesignSystematic Reviews as TopicHepatologyHistologyPublic health

Identifiers

PMID36737085
PMCPMC9900053
OpenAlexW4319078539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.