Evidence map›Paper›PMID 36736954›Full record

ArticleThe journal of allergy and clinical immunology. In practice2023

Racial and Ethnic Disparities in Allergen Immunotherapy Prescription for Allergic Rhinitis.

Sunjay Modi, Matthew R Norris, Victoria Nguyen, Robert Bower, Timothy J Craig, Taha Al-Shaikhly

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
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  4. Health Disparities in Rhinology-A Scoping Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sunjay ModiDepartment of Medicine, Section of Allergy, Asthma and Immunology, Penn State College of Medicine, Hershey, Pa. Electronic address: smodi@pennstatehealth.psu.edu.
Matthew R NorrisDepartment of Medicine, Section of Allergy, Asthma and Immunology, Penn State College of Medicine, Hershey, Pa.
Victoria NguyenDepartment of Medicine, Penn State College of Medicine, Hershey, Pa.
Robert BowerDepartment of Medicine, Penn State College of Medicine, Hershey, Pa.
Timothy J CraigDepartment of Medicine, Section of Allergy, Asthma and Immunology, Penn State College of Medicine, Hershey, Pa.
Taha Al-ShaikhlyDepartment of Medicine, Section of Allergy, Asthma and Immunology, Penn State College of Medicine, Hershey, Pa.
Penn State Milton S. Hershey Medical Center · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
NCATS NIH HHS UL1 TR002014
6 · The paper itself

Abstract

backgroundRacial and ethnic differences exist in the severity of various atopic diseases including allergic rhinitis (AR). Patients of under-represented races and ethnicities may be subjected to disparate subcutaneous allergen immunotherapy (SCIT) prescription practices.

objectiveTo explore the racial and ethnic disparities in the use of SCIT among patients with AR.

methodsIn this retrospective matched cohort study, we used the TriNetX US Collaborative Network, a multicenter electronic health record-based database to identify patients with AR 18 years and older. Patients were grouped according to their racial and ethnic identification. Study groups were matched for baseline demographics, atopic comorbidities, heart diseases and utilization of β-blockers, and angiotensin-converting enzyme inhibitors. The proportion of patients of under-represented racial and ethnic groups started on SCIT was contrasted to the non-Hispanic White cohort.

resultsWe identified 1,038,000 patients with AR; the mean age (±standard deviation) at the index was 49.7 (±16.1) years, and 64.6% were female. Ethnicity information was available from 87.3% of patients, and the majority (92.3%) were non-Hispanic. Over a 3-year observation period, fewer Black patients (relative risk [RR], 0.40; 95% confidence interval [CI], 0.33-0.48) and Hispanic patients (RR, 0.80; 95% CI, 0.64-0.99) were started on SCIT compared with non-Hispanic White patients. The proportions of Asian patients who were initiated on SCIT tended to be lower when compared with non-Hispanic White patients (RR, 0.69; 95% CI, 0.47-1.009).

conclusionsIn the United States, differences in SCIT prescription exist between Black and Hispanic patients relative to White patients. Barriers to treatment should be explored and mitigated.

Indexed as

Rhinitis, AllergicAdultAgedCohort StudiesDesensitization, ImmunologicEthnicityFemaleHumansMaleMiddle AgedRetrospective StudiesUnited StatesAITAllergen immunotherapyAllergic rhinitisDisparities in health careEthnic disparitiesRacial disparitiesSCITSubcutaneous allergen immunotherapy

Identifiers

PMID36736954
PMCPMC10164679
OpenAlexW4318821466

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.