ArticleResuscitation2023
High central venous pressure amplitude predicts successful defibrillation in a porcine model of cardiac arrest.
Article in Resuscitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Pressure Measurements Obtained from Intraosseous Access: Potential Clinical Applications Explored Using a Porcine Model.Journal of cardiovascular translational research · 2026Article
- Realtime detection of spontaneous circulation in humans during cardiopulmonary resuscitation using a continuous hands-free carotid Doppler: a pilot study.Resuscitation plus · 2025Article
- Association of diastolic blood pressure with coronary perfusion pressure during resuscitation in pediatric swine.Pediatric research · 2025Article
- A new method to predict return of spontaneous circulation by peripheral intravenous analysis during cardiopulmonary resuscitation: a rat model pilot study.Intensive care medicine experimental · 2024Article
- Endovascular aortic occlusion improves return of spontaneous circulation after longer periods of cardiopulmonary resuscitation: A translational study in pigs.Resuscitation plus · 2024Article
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
aimIncreasing venous return during cardiopulmonary resuscitation (CPR) has been shown to improve hemodynamics during CPR and outcomes following cardiac arrest (CA). We hypothesized that a high central venous pressure amplitude (CVP-A), the difference between the maximum and minimum central venous pressure during chest compressions, could serve as a robust predictor of return of spontaneous circulation (ROSC) in addition to traditional measurements of coronary perfusion pressure (CPP) and end-tidal CO
methodsAfter 10 min of ventricular fibrillation, 9 anesthetized and intubated female pigs received mechanical chest compressions with active compression/decompression (ACD) and an impedance threshold device (ITD). CPP, CVP-A and etCO
resultsFive animals out of 9 experienced ROSC. CVP-A showed a statistically significant difference (p = 0.003) between the two groups during 3 min of CPR before defibrillation compared to CPP (p = 0.056) and etCO
conclusionIn our study, CVP-A was a potentially useful predictor of successful defibrillation and return of spontaneous circulation. Overall, CVP-A could serve as a marker for prediction of ROSC with increased venous return and thereby monitoring the beneficial effects of ACD and ITD.
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