Evidence map›Paper›PMID 36736191›Full record

ArticleJournal of psychosomatic research2023

Persistent physical symptoms after COVID-19 infection and the risk of Somatic Symptom Disorder.

Mathilde Horn, Marielle Wathelet, Ali Amad, Niels Martignène, Thomas Lathiere, Kamélia Khelfaoui, Margot Rousselle, Oumaïma El Qaoubii, Fanny Vuotto, Karine Faure and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of psychosomatic research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Mathilde HornUniv. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, F-59000 Lille, France; CHU Lille, Pôle de Psychiatrie, F-59000 Lille, France. Electronic address: horn.mathilde@gmail.com.
Marielle WatheletUniv. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, F-59000 Lille, France; CHU Lille, Pôle de Psychiatrie, F-59000 Lille, France; Centre National de Ressources et de Résilience Lille-Paris (CN2R), Lille F-59000, France.
Ali AmadUniv. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, F-59000 Lille, France; CHU Lille, Pôle de Psychiatrie, F-59000 Lille, France; Department of Neuroimaging, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.
Niels MartignèneCentre National de Ressources et de Résilience Lille-Paris (CN2R), Lille F-59000, France.
Thomas LathiereCHU Lille, Pôle de Psychiatrie, F-59000 Lille, France.
Kamélia KhelfaouiCHU Lille, Pôle de Psychiatrie, F-59000 Lille, France.
Margot RousselleCHU Lille, Pôle de Psychiatrie, F-59000 Lille, France.
Oumaïma El QaoubiiCHU Lille, Pôle de Psychiatrie, F-59000 Lille, France.
Fanny VuottoService de Maladies Infectieuses et Tropicales, CHU Lille, Equipe OpInfIELD Infections Opportunistes, Immunité, Environnement & Maladies Pulmonaires, Centre Infection et Inflammation, Inserm U1019; CNRS UMR9017; Université de Lille, Institut Pasteur de Lille, CHU de Lille, France.
Karine FaureService de Maladies Infectieuses et Tropicales, CHU Lille, Equipe OpInfIELD Infections Opportunistes, Immunité, Environnement & Maladies Pulmonaires, Centre Infection et Inflammation, Inserm U1019; CNRS UMR9017; Université de Lille, Institut Pasteur de Lille, CHU de Lille, France.
Coralie CreupelandtCentre National de Ressources et de Résilience Lille-Paris (CN2R), Lille F-59000, France.
Guillaume VaivaUniv. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, F-59000 Lille, France; CHU Lille, Pôle de Psychiatrie, F-59000 Lille, France; Centre National de Ressources et de Résilience Lille-Paris (CN2R), Lille F-59000, France.
Thomas FovetUniv. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, F-59000 Lille, France; CHU Lille, Pôle de Psychiatrie, F-59000 Lille, France; Centre National de Ressources et de Résilience Lille-Paris (CN2R), Lille F-59000, France.
Fabien D'HondtUniv. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, F-59000 Lille, France; CHU Lille, Pôle de Psychiatrie, F-59000 Lille, France; Centre National de Ressources et de Résilience Lille-Paris (CN2R), Lille F-59000, France.
Université de Lille · FRInserm · FRCentre Hospitalier Universitaire de Lille · FRCentre National de la Recherche Scientifique · FRKing's College London · GBLille Neurosciences & Cognition

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvidence shows that many patients with COVID-19 present persistent symptoms after the acute infection. Some patients may be at a high risk of developing Somatic Symptom Disorder (SSD), in which persistent symptoms are accompanied by excessive and disproportionate health-related thoughts, feelings and behaviors regarding these symptoms. This study assessed the frequency of persistent physical symptoms and SSD and their associated factors in patients with confirmed COVID-19.

methodsWe conducted a longitudinal retrospective study after the first two French lockdowns at the Lille University Hospital (France), including all patients with confirmed COVID-19. Persistent physical symptoms and excessive preoccupations for these symptoms were measured 8 to 10 months after the onset of COVID-19. The combination of the Patient Health Questionnaire-15 and the Somatic Symptom Disorder-B Criteria Scale was used to identify the individuals likely to present with SSD. Two linear regression models were performed to identify sociodemographic and medical risk factors of SSD.

resultsAmong the 377 patients with a laboratory-confirmed diagnosis, 220 (58.4%) completed the questionnaires. Sixty-five percent of the 220 included patients required hospitalization, 53.6% presented at least one persistent physical symptom and 10.4% were considered to present SSD. Female sex, older age, infection during the second wave and having probable PTSD were significantly associated with the severity of SSD and SSD was associated with a significantly higher healthcare use.

conclusionsThe identification of SSD should encourage clinicians to move beyond the artificial somatic/psychiatric dualism and contribute to a better alliance based on multi-disciplinary care.

Indexed as

COVID-19Medically Unexplained SymptomsCommunicable Disease ControlFemaleHumansRetrospective StudiesSomatoform DisordersCOVID-19Long COVID, post-acute sequelae of COVID-19Post-COVID conditionPost-traumatic stress disorderSomatic Symptom Disorder

Identifiers

PMID36736191
PMCPMC9876030
OpenAlexW4318035820

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.