Evidence map›Paper›PMID 36736058›Full record

SynthesisPoultry science2023

A meta-analysis of the effects of clay mineral supplementation on alkaline phosphatase, broiler health, and performance.

Mohammad Miftakhus Sholikin, Sadarman, Agung Irawan, Ahmad Sofyan, Anuraga Jayanegara, Barlah Rumhayati, Cecep Hidayat, Danung Nur Adli, Hardi Julendra, Hendra Herdian and 14 more

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Poultry science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Asian palmyra palm (Open veterinary journal · 2025
    Article
  6. Zeolite and Neurodegenerative Diseases.Molecules (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 5 institutions in 2 countries.

Mohammad Miftakhus SholikinResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia; Meta-Analysis in Plant Science (MAPS) Research Group, Bandung 40621, Indonesia; Center for Tropical Animal Studies (CENTRAS), The Institute of Research and Community Empowerment of IPB (LPPM IPB), Bogor 16680, Indonesia. Electronic address: mohammad.miftakhus.sholikin@gmail.com.
SadarmanDepartment of Animal Science, State Islamic University of Sultan Syarif Kasim Riau, Pekanbaru 28293, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Agung IrawanVocational School, Universitas Sebelas Maret, Surakarta 57126, Indonesia; Department of Animal and Rangeland Sciences, Oregon State University, Corvallis 97331, OR, USA; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Ahmad SofyanResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Anuraga JayanegaraDepartment of Nutrition and Feed Technology, Faculty of Animal Science, IPB University, Bogor 16680, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Barlah RumhayatiChemistry Department, Faculty of Science, Brawijaya University, Malang 65145, Indonesia.
Cecep HidayatResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Danung Nur AdliFeed and Animal Nutrition Department, Faculty of Animal Science, Universitas Brawijaya, Malang 65145, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Hardi JulendraResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia.
Hendra HerdianResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Ifa ManzilaResearch Center for Horticultural and Estate Corps, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia.
Mohammad Firdaus HudayaResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia.
Muhammad Ainsyar HarahapResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia.
Novia QomariyahResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Rahmat BudiartoDepartment of Agronomy, Faculty of Agriculture, Universitas Padjadjaran, Jatinangor Sumedang 45363, Indonesia; Meta-Analysis in Plant Science (MAPS) Research Group, Bandung 40621, Indonesia.
Rantan KrisnanResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Santiananda Arta AsmarasariResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia.
Sari Yanti HayantiResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia.
Teguh WahyonoResearch Center for Food Technology and Processing, National Research and Innovation Agency (BRIN), Research Organization for Agriculture and Food, Gunungkidul 55861, Indonesia; Animal Feed and Nutrition Modelling (AFENUE) Research Group, IPB University, Bogor 16680, Indonesia.
Tri Puji PriyatnoResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia.
Tri UjilestariResearch Center for Food Technology and Processing, National Research and Innovation Agency (BRIN), Research Organization for Agriculture and Food, Gunungkidul 55861, Indonesia.
Windu NegaraResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia.
Wulandari WulandariResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Bogor 16915, Indonesia.
Nahrowi NahrowiDepartment of Nutrition and Feed Technology, Faculty of Animal Science, IPB University, Bogor 16680, Indonesia; Center for Tropical Animal Studies (CENTRAS), The Institute of Research and Community Empowerment of IPB (LPPM IPB), Bogor 16680, Indonesia.
IPB University · IDIndonesian Agency for Agricultural Research and Development · IDUniversity of Brawijaya · IDPadjadjaran University · IDSebelas Maret University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The crucial constraint in the broiler production sector is feed efficiency; many feed additives have been widely employed to increase broiler growth. Nonetheless, some of these substances exacerbate health and animal-based food product safety concerns. This meta-analysis examines the effect of clay minerals on alkaline phosphatase (ALP), broiler health, and performance. Metadata was constructed from 369 data items that were harvested from 86 studies. The addition of clay minerals was set as a fixed effect and the difference between experiments was established as a random effect. The metadata were fitted using a linear mixed model. Due to the presence of clay minerals, growth performance as assessed by body weight (BW), average daily gain (ADG), and performance efficiency index (PEI) increased significantly (P < 0.01). In the total period, the increases of BW, ADG, and PEI were 4.12 g, 0.0714 g/d, and 0.648, respectively, per unit of clay minerals added. Clay minerals did not affect blood serum parameters (e.g., ALP and calcium). The IgA and IgM concentrations in the jejunum and ileum were significantly greater (P < 0.01) in the starter phase. Among clay minerals, broilers fed diets with aluminosilicate, halloysite, kaolin, and zeolite consistently exhibited higher (P < 0.05) BW, ADG, PEI, and lower feed conversion ratio (P < 0.05) in the finisher phase. Aluminosilicate was the only clay that increased (P < 0.05) secretory IgA concentration in both jejunum and ileum. In conclusion, clay minerals could be used as a growth promoter, especially during the finisher phase, without adversely affecting feed intake, liver function, and mineral metabolism in broiler chickens. Aluminosilicate was superior in improving the mucosal immunity status of broiler chickens.

Indexed as

Alkaline PhosphataseChickensAluminum SilicatesAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsBody WeightClayDietDietary SupplementsMineralsAlkaline PhosphatasealuminosilicateAluminum SilicatesClayMineralsbroiler chickensclay mineralgrowth promotersmeta-analysiszeolite

Identifiers

PMID36736058
PMCPMC10014353
OpenAlexW4313332894

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.