ArticlePloS one2023
Early detection of depression using a conversational AI bot: A non-clinical trial.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of Chatbots in Mental Health Screening and Assessment: Systematic Review.JMIR mental health · 2026Pooled it
- Usability Comparison Among Healthy Participants of an Anthropomorphic Digital Human and a Text-Based Chatbot as a Responder to Questions on Mental Health: Randomized Controlled Trial.JMIR human factors · 2024Trial
- AI-Based Measurement Tools for Intrinsic Capacity in Older Adults: Scoping Review.Journal of medical Internet research · 2026Article
- A scoping review of the use of artificial intelligence as a psychological assessment tool.Translational psychiatry · 2026Article
- Feasibility and user evaluation of HopeBot: An LLM-powered conversational chatbot for depression screening.PLOS digital health · 2026Article
- When a chatbot asks "How are you?": A cross-sectional study of AI call conversations and depressive symptom detection among older adults in rural South Korea.BMC geriatrics · 2026Article
- An Ubuntu-guided large language model framework for cognitive behavioral mental health dialogue.Frontiers in digital health · 2026Article
- The Use of Artificial Intelligence for Personalized Treatment in Psychiatry.Current psychiatry reports · 2025Review
- A Scoping Review of AI-Driven Digital Interventions in Mental Health Care: Mapping Applications Across Screening, Support, Monitoring, Prevention, and Clinical Education.Healthcare (Basel, Switzerland) · 2025Review
- Integrative approaches to depression in end-stage renal disease: insights into mechanisms, impacts, and pharmacological strategies.Frontiers in pharmacology · 2025Review
- Bayesian mediation analysis using patient-reported outcomes from AI chatbots to infer causal pathways in clinical trials.PloS one · 2025Article
- Development of a questionnaire for assessing the use of ChatGPT in primary and secondary disease prevention.Frontiers in public health · 2025Article
- Roles, Users, Benefits, and Limitations of Chatbots in Health Care: Rapid Review.Journal of medical Internet research · 2024Review
- A review on the efficacy of artificial intelligence for managing anxiety disorders.Frontiers in artificial intelligence · 2024Review
- Improving Mental Health Outcomes in Patients with Major Depressive Disorder in the Gulf States: A Review of the Role of Electronic Enablers in Monitoring Residual Symptoms.Journal of multidisciplinary healthcare · 2024Review
- Review
- Systematic review of artificial intelligence enabled psychological interventions for depression and anxiety: A comprehensive analysis.Industrial psychiatry journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArtificial intelligence (AI) has gained momentum in behavioural health interventions in recent years. However, a limited number of studies use or apply such methodologies in the early detection of depression. A large population needing psychological-intervention is left unidentified due to barriers such as cost, location, stigma and a global shortage of health workers. Therefore, it is essential to develop a mass screening integrative approach that can identify people with depression at its early stage to avoid a potential crisis.
objectivesThis study aims to understand the feasibility and efficacy of using AI-enabled chatbots in the early detection of depression.
methodsWe use Dialogflow as a conversation interface to build a Depression Analysisn (DEPRA) chatbot. A structured and authoritative early detection depression interview guide, which contains 27 questions combining the structured interview guide for the Hamilton Depression Scale (SIGH-D) and the inventory of depressive symptomatology (IDS-C), underpins the design of the conversation flow. To attain better accuracy and a wide variety of responses, we train Dialogflow with the utterances collected from a focus group of 10 people. The occupation of the focus group members included academics and HDR candidates who are conscious, vigilant and have a clear understanding of the questions. In addition, DEPRA is integrated with a social media platform to provide practical access to all the participants. For the non-clinical trial, we recruited 50 participants aged between 18 and 80 from across Australia. To evaluate the practicability and performance of DEPRA, we also asked participants to submit a user satisfaction survey at the end of the conversation.
resultsA sample of 50 participants, with an average age of 34.7 years, completed this non-clinical trial. More than half of the participants (54%) are male and the major ethnicities are Asian (63%), Middle Eastern (25%), and others 12%. The first group comprises professional academic staff and HDR candidates, the second and third groups comprise relatives, friends, and volunteers who were recruited via social media promotions. DEPRA uses two scientific scoring systems, QIDS-SR and IDS-SR to verify the results of early depression detection. As the results indicate, both scoring systems return a similar outcome with slight variations for different depression levels. According to IDS-SR, 30% of participants were healthy, 14% mild, 22% moderate, 14% severe, and 20% very severe. QIDS-SR suggests 32% were healthy, 18% mild, 10% moderate, 18% severe, and 22% very severe. Furthermore, the overall satisfaction rate of using DEPRA was 79% indicating that the participants had a high rate of user satisfaction and engagement.
conclusionDEPRA shows promises as a feasible option for developing a mass screening integrated approach for early detection of depression. Although the chatbot is not intended to replace the functionality of mental health professionals, it does show promise as a means of assisting with automation and concealed communication with verified scoring systems.
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