Evidence map›Paper›PMID 36735216›Full record

ArticleDrug delivery and translational research2023

Assessment of formulation variables of poor water soluble diacerein for its improved loading and anti-inflammatory activity.

Maryam Shabbir, Kashif Barkat, Muhammad Umer Ashraf, Uzair Nagra, Syed Nisar Hussain Shah

Abstract read
PubMed Publisher
In one paragraph

Article in Drug delivery and translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maryam ShabbirFaculty of Pharmacy, University of Lahore, Lahore, Punjab, Pakistan.ORCID http://orcid.org/0000-0002-9308-5175
Kashif BarkatFaculty of Pharmacy, University of Lahore, Lahore, Punjab, Pakistan. dr.kashif2009@gmail.com.ORCID http://orcid.org/0000-0003-4038-6035
Muhammad Umer AshrafFaculty of Pharmacy, University of Lahore, Lahore, Punjab, Pakistan.
Uzair NagraFaculty of Pharmacy, University of Lahore, Lahore, Punjab, Pakistan.ORCID http://orcid.org/0000-0002-7549-8195
Syed Nisar Hussain ShahFaculty of Pharmacy, University of Lahore, Lahore, Punjab, Pakistan.
University of Lahore · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dissolving microneedles have become a popular method for percutaneous administrationof drugs. However, loading poorly soluble drugs into water-based dissolving microneedles remains a challenge. In view of this, we aimed to improve Diacerein (DCN) solubility formulating dissolving microneedles. DCN microsuspension was created by high-speed homogenization with organic solvents or wet milling with Tween 80 as a stabilizer (LD

Indexed as

SkinWaterAdministration, CutaneousAnti-Inflammatory AgentsDrug Delivery SystemsNeedlesSolubilityAnti-Inflammatory AgentsWaterDiacereinDissolving microneedleMicrosuspensionSkin insertionSolubility

Identifiers

PMID36735216
OpenAlexW4319058061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.