Evidence map›Paper›PMID 36735111›Full record

Trial reportJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2023

Device-detected atrial fibrillation in a large remote-monitored cohort: implications for anticoagulation and need for new pathways of service delivery.

Catherine J O'Shea, Anthony G Brooks, Melissa E Middeldorp, Curtis Harper, Jeroen M Hendriks, Andrea M Russo, James V Freeman, Rakesh Gopinathannair, Niraj Varma, Thomas F Deering and 2 more

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. The digital journey: 25 years of digital development in electrophysiology from an Europace perspective.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Catherine J O'SheaCentre for Heart Rhythm Disorders, University of Adelaide, Adelaide, Australia.
Anthony G BrooksCentre for Heart Rhythm Disorders, University of Adelaide, Adelaide, Australia.
Melissa E MiddeldorpCentre for Heart Rhythm Disorders, University of Adelaide, Adelaide, Australia.
Curtis HarperPaceMate, Bradenton, FL, USA.
Jeroen M HendriksCentre for Heart Rhythm Disorders, University of Adelaide, Adelaide, Australia.
Andrea M RussoCooper Medical School of Rowan University, Camden, NJ, USA.
James V FreemanDepartment of Medicine, Yale University School of Medicine, New Haven, CT, USA.
Rakesh GopinathannairKansas City Heart Rhythm Institute, Kansas City, MO, USA.
Niraj VarmaCleveland Clinic, Cleveland, OH, USA.
Thomas F DeeringPiedmont Heart Institute, Atlanta, GA, USA.
Kevin CampbellHealth First Heart and Vascular, Melbourne, FL, USA.
Prashanthan SandersCentre for Heart Rhythm Disorders, University of Adelaide, Adelaide, Australia. prash.sanders@adelaide.edu.au.ORCID http://orcid.org/0000-0003-3803-8429
Royal Adelaide Hospital · AUCleveland Clinic · USCooper Medical School of Rowan University · USHealth First · USHeart Rhythm Society · USPiedmont Atlanta Hospital · USThe University of Adelaide · AUYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

backgroundRemote monitoring (RM) can facilitate early detection of subclinical and symptomatic atrial fibrillation (AF), providing an opportunity to evaluate the need for stroke prevention therapies. We aimed to characterize the burden of RM AF alerts and its impact on anticoagulation of patients with device-detected AF.

methodsConsecutive patients with a cardiac implantable electronic device, at least one AF episode, undergoing RM were included and assigned an estimated minimum CHA

resultsFrom 7651 individual, 389,188 AF episodes were identified, 3120 (40.8%) permanent pacemakers, 2260 (29.5%) implantable loop recorders (ILRs), 987 (12.9%) implantable cardioverter defibrillators, 968 (12.7%) cardiac resynchronization therapy (CRT) defibrillators, and 316 (4.1%) CRT pacemakers. ILRs transmitted 48.8% of all AF episodes. At twelve-months, 3404 (44.5%) AF < 6 min, 1367 (17.9%) 6 min-6 h, 1206 (15.8%) 6-24 h, and 1674 (21.9%) ≥ 24 h. A minimum CHA

conclusionsDespite being intensively managed via RM software system incorporating cues for anticoagulation, a substantial proportion of patients with increased stroke risk remained unanticoagulated after a device-detected AF episode of significant duration. These data highlight the need for improved clinical response pathways and an integrated care approach to RM.

trial registrationAustralian New Zealand Clinical Trial Registry: ACTRN12620001232921.

Indexed as

Atrial FibrillationDefibrillators, ImplantablePacemaker, ArtificialAnticoagulantsAustraliaHumansRisk FactorsAnticoagulantsAnticoagulationAtrial fibrillationCardiac implantable electronic deviceRemote monitoring

Identifiers

PMID36735111
PMCPMC10547627
OpenAlexW4319063580

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.