Evidence map›Paper›PMID 36734673›Full record

ArticleInternational journal of experimental pathology2023

The frequency of dysplastic branching crypts in colorectal polypoid tubular adenomas.

Carlos A Rubio, Michael Vieth, Corinna Lang-Schwarz

Open access · hybridAbstract read
In one paragraph

Article in International journal of experimental pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Carlos A RubioDepartment of Pathology, Karolinska Institute, University Hospital, Stockholm, Sweden.ORCID 0000-0003-3879-5729
Michael ViethInstitute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Bayreuth, Germany.
Corinna Lang-SchwarzInstitute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Bayreuth, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysplastic crypt branching (DCB) was recently found in ulcerative colitis-associated dysplasia. The aim was to assess the frequency and the branching phenotype of DCB in polypoid colorectal tubular adenomas (TA). A total of 3956 DCB were found in the 139 TA: 98% were in asymmetric branching (DCAB) and the remaining 2% in symmetric branching (DCSB). A linear correlation was found between DCB frequency and the increasing digital size in TA (p < .05). Using a digital ruler, adenomas were divided into small TA (<5 mm) and larger TA (≥5 mm). The difference between the frequency of DCB in small TA (n = 75) vs. larger TA (n = 64), was significant (p < .05). DCB frequency was not influenced by age, gender or TA localization. In the normal colorectal mucosa (≈2 m

Indexed as

AdenomaColitis, UlcerativeColorectal NeoplasmsHumansHyperplasiaIntestinal MucosaPhenotypecolondysplastic crypt branchingrectumsizetubular adenoma

Identifiers

PMID36734673
PMCPMC10182366
OpenAlexW4319063138

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.