Evidence map›Paper›PMID 36734672›Full record

ArticlePediatric obesity2023

Prenatal tobacco and cannabis co-exposure and offspring obesity development from birth to mid-childhood.

Kai Ling Kong, Jin-Kyung Lee, Shannon Shisler, Panayotis K Thanos, Marilyn A Huestis, Larry Hawk, Rina D Eiden

Open access · greenAbstract read
In one paragraph

Article in Pediatric obesity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. A Qualitative Investigation of Nicotine and Tobacco use in Young Pregnant and Birthing Sexual Minority People.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kai Ling KongBaby Health Behavior Lab, Division of Health Services and Outcomes Research, Children's Mercy Research Institute, Children's Mercy Hospital, Kansas City, Missouri, USA.
Jin-Kyung LeeDepartment of Psychology and The Social Science Research Institute, The Pennsylvania State University, Pennsylvania, USA.
Shannon ShislerDepartment of Psychology, University at Buffalo, State University of New York, Buffalo, New York, USA.
Panayotis K ThanosDepartment of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, State University of New York, Buffalo, New York, USA.
Marilyn A HuestisInstitute on Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Larry HawkDepartment of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, State University of New York, Buffalo, New York, USA.
Rina D EidenDepartment of Psychology and The Social Science Research Institute, The Pennsylvania State University, Pennsylvania, USA.
Pennsylvania State University · USUniversity at Buffalo, State University of New York · USChildren's Mercy Hospital · USJacobs Institute · USThomas Jefferson University · US

Funding

Prenatal & ETS Exposure: Effects on Child RegulationR01DA019632 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EIDEN, RINA D · 2006 to 2016
$5.8M
Prenatal Tobacco and Cannabis Exposure: A Translational StudyR33DA045640 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EIDEN, RINA D, THANOS, PANAYOTIS K · 2021 to 2023
$999k
Prenatal Tobacco and Cannabis Exposure: A Translational StudyR21DA045640 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EIDEN, RINA D, THANOS, PANAYOTIS K · 2018 to 2019
$434k
NIDA NIH HHS R01 DA019632NIDA NIH HHS R01DA019632NIDA NIH HHS R21 DA045640NIDA NIH HHS R21DA04564002NIDA NIH HHS R33 DA045640
6 · The paper itself

Abstract

backgroundAlthough the association between prenatal tobacco exposure and child obesity risk is well-established, less is known about co-exposure to tobacco and cannabis.

objectiveDetermine the relation between prenatal substance co-exposure and obesity risk.

methodsIn a diverse sample of pregnant women, we examined the association between prenatal substance exposure (tobacco-only and co-exposure) and child BMI (kg/m

resultsMultilevel models demonstrated that children in both exposure groups had a steeper increase in BMI trajectory from birth to mid-childhood and among co-exposed children, girls had a steeper increase than boys. Odds ratio of having obesity by mid-childhood was 12 times higher among those co-exposed than non-exposed. Co-exposure led to significantly greater fat mass and fat mass % compared with no exposure, but exposure to only tobacco was no different than no exposure.

conclusionsResults highlight potentiating effects of cannabis exposure in the context of maternal tobacco use in pregnancy on obesity risk and the importance of multi-method assessments of obesity.

Indexed as

CannabisPediatric ObesityPrenatal Exposure Delayed EffectsAdiposityBody Mass IndexChildFemaleHumansMaleOverweightPregnancyTobacco Productsbody compositioncannabisoffspring obesityprenatal substance exposuretobacco

Identifiers

PMID36734672
PMCPMC10288513
OpenAlexW4319057798

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.