Evidence map›Paper›PMID 36734644›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2022

Larger Perioperative Opioid Prescriptions Lead to Prolonged Opioid Use After Hand and Upper Extremity Surgery: A Multicenter Analysis.

Clay B Townsend, Justin A Ly, Ryan Judy, Matthew B Sherman, Nick Elmer, Christine Conroy, Hesham M Abdelfattah, Mark K Solarz, Katharine Woozley, Asif M Ilyas

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Clay B TownsendFrom the Rothman Orthopaedic Institute (Dr. Townsend, Mr. Sherman, and Dr. Ilyas); the Lewis Katz School of Medicine, Temple University (Mr. Ly); Orthopaedic Surgery and Sports Medicine, Temple University Hospital (Dr. Judy, Dr. Abdelfattah, and Dr. Solarz); the Department of Orthopaedics, Einstein Healthcare Network (Dr. Conroy and Dr. Woozley); the Rothman Orthopaedic Institute Foundation for Opioid Research & Education (Dr. Ilyas); and the Sidney Kimmel Medical College, Thomas Jefferson University (Mr. Elmer and Dr. Ilyas), Philadelphia, PA.ORCID 0000-0002-7280-6025
Justin A Ly
Ryan Judy
Matthew B Sherman
Nick Elmer
Christine Conroy
Hesham M Abdelfattah
Mark K Solarz
Katharine Woozley
Asif M Ilyas
Defence Research and Development Organisation · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe opioid epidemic remains an ongoing public health crisis. The purpose of this study was to investigate whether surgeons' prescribing patterns of the initial postoperative opioid prescription predispose patients to prolonged opioid use after upper extremity surgery.

methodsThis multicenter retrospective study was done at three academic institutions. Patients who underwent carpal tunnel release, basal joint arthroplasty, and distal radius fracture open reduction and internal fixation over a 1.5-year period were included. Opioid prescription data were obtained from the Pennsylvania Prescription Drug Monitoring Program website.

resultsPostoperatively, 30.1% of the patients (191/634) filled ≥1 additional opioid prescription, and 14.0% (89/634) experienced prolonged opioid use 3 to 6 months postoperatively. Patients who filled an additional prescription postoperatively were initially prescribed significantly more pills (P = 0.001), a significantly longer duration prescription (P = 0.009), and a significantly larger prescription in total milligram morphine equivalents (P = 0.002) than patients who did not fill additional prescriptions. Patients who had prolonged opioid use were prescribed a significantly longer duration prescription (P = 0.026) than those without prolonged use.

conclusionLarger and longer duration of initial opioid prescriptions predisposed patients to continued postoperative opioid use. These findings emphasize the importance of safe and evidence-based prescribing practices to prevent the detrimental effects of opioid use after orthopaedic surgery.

Indexed as

Analgesics, OpioidOpioid-Related DisordersDrug PrescriptionsHandHumansPostoperative PainRetrospective StudiesAnalgesics, Opioid

Identifiers

PMID36734644
PMCPMC9592474
OpenAlexW4319063416

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.