Evidence map›Paper›PMID 36734487›Full record

ArticleThe American journal of sports medicine2023

Meniscal and Articular Cartilage Predictors of Outcome After Revision ACL Reconstruction: A 6-Year Follow-up Cohort Study.

MARS Group, Rick W Wright, Laura J Huston, Amanda K Haas, Jacquelyn S Pennings, Christina R Allen, Daniel E Cooper, Thomas M DeBerardino, Warren R Dunn, Brett Brick A Lantz and 82 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of sports medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Risk factors for ACL revision failure and optimum graft size for revision anterior cruciate ligament reconstruction.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

92 authors at 20 institutions in 2 countries.

MARS Group
Rick W WrightVanderbilt University, Nashville, Tennessee, USA.
Laura J HustonVanderbilt University, Nashville, Tennessee, USA.
Amanda K HaasWashington University in St Louis, St Louis, Missouri, USA.
Jacquelyn S PenningsVanderbilt University, Nashville, Tennessee, USA.
Christina R AllenYale University, New Haven, Connecticut, USA.
Daniel E CooperWB Carrell Memorial Clinic, Dallas, Texas, USA.
Thomas M DeBerardinoThe San Antonio Orthopaedic Group, San Antonio, Texas, USA.
Warren R DunnTexas Orthopedic Hospital, Houston, Texas, USA.
Brett Brick A LantzSlocum Research and Education Foundation, Eugene, Oregon, USA.
Kurt P SpindlerCleveland Clinic, Cleveland, Ohio, USA.
Michael J StuartMayo Clinic, Rochester, Minnesota, USA.
John P AlbrightUniversity of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Annunziato Ned AmendolaDuke University, Durham, North Carolina, USA.
Jack T AndrishCleveland Clinic, Cleveland, Ohio, USA.
Christopher C AnnunziataCommonwealth Orthopaedics and Rehabilitation, Arlington, Virginia, USA.
Robert A ArcieroUniversity of Connecticut Health Center, Farmington, Connecticut, USA.
Bernard R BachRush University Medical Center, Chicago, Illinois, USA.
Champ L BakerThe Hughston Clinic, Columbus, Georgia, USA.
Arthur R Bartolozzi3B Orthopaedics, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
Keith M BaumgartenOrthopedic Institute, Sioux Falls, South Dakota, USA.
Jeffery R BechlerUniversity Orthopaedic Associates LLC, Princeton, New Jersey, USA.
Jeffrey H BergTown Center Orthopaedic Associates, Reston, Virginia, USA.
Geoffrey A BernasState University of New York at Buffalo, Buffalo, NY.
Stephen F BrockmeierUniversity of Virginia, Charlottesville, Virginia, USA.
Robert H BrophyWashington University in St Louis, St Louis, Missouri, USA.
Charles A Bush-JosephRush University Medical Center, Chicago, Illinois, USA.
J Brad ButlerOrthopedic and Fracture Clinic, Portland, Oregon, USA.
John D CampbellBridger Orthopedic and Sports Medicine, Bozeman, Montana, USA.
James L CareyUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
James E CarpenterUniversity of Michigan, Ann Arbor, Michigan, USA.
Brian J ColeRush University Medical Center, Chicago, Illinois, USA.
Jonathan M CooperHealthPartners Specialty Center, St Paul, Minnesota, USA.
Charles L CoxVanderbilt University, Nashville, Tennessee, USA.
R Alexander CreightonUniversity of North Carolina Medical Center, Chapel Hill, North Carolina, USA.
Diane L DahmMayo Clinic, Rochester, Minnesota, USA.
Tal S DavidSynergy Specialists Medical Group, San Diego, California, USA.
David C FlaniganThe Ohio State University, Columbus, Ohio, USA.
Robert W FrederickThe Rothman Institute/Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Theodore J GanleyChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Elizabeth A GarofoliWashington University in St Louis, St Louis, Missouri, USA.
Charles J GattUniversity Orthopaedic Associates LLC, Princeton, New Jersey, USA.
Steven R GechaPrinceton Orthopaedic Associates, Princeton, New Jersey, USA.
James Robert GiffinFowler Kennedy Sport Medicine Clinic, University of Western Ontario, London, Ontario, Canada.
Sharon L HameDavid Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Jo A HannafinHospital for Special Surgery, New York, New York, USA.
Christopher D HarnerUniversity of Texas Health Center, Houston, Texas, USA.
Norman Lindsay HarrisGrand River Health, Rifle, Colorado, USA.
Keith S HechtmanUHZ Sports Medicine Institute, Coral Gables, Florida, USA.
Elliott B HershmanLenox Hill Hospital, New York, New York, USA.
Rudolf G HoellrichSlocum Research and Education Foundation, Eugene, Oregon, USA.
David C JohnsonNational Sports Medicine Institute, Leesburg, Virginia, USA.
Timothy S JohnsonNational Sports Medicine Institute, Leesburg, Virginia, USA.
Morgan H JonesCleveland Clinic, Cleveland, Ohio, USA.
Christopher C KaedingThe Ohio State University, Columbus, Ohio, USA.
Ganesh V KamathUniversity of North Carolina Medical Center, Chapel Hill, North Carolina, USA.
Thomas E KlootwykMethodist Sports Medicine, Indianapolis, Indiana, USA.
Bruce A LevyMayo Clinic Rochester, Minnesota, USA.
C Benjamin MaUniversity of California, San Francisco, California, USA.
G Peter MaiersMethodist Sports Medicine Center, Indianapolis, Indiana, USA.
Robert G MarxHospital for Special Surgery, New York, New York, USA.
Matthew J MatavaWashington University in St Louis, St Louis, Missouri, USA.
Gregory M MathienKnoxville Orthopaedic Clinic, Knoxville, Tennessee, USA.
David R McAllisterDavid Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Eric C McCartyUniversity of Colorado Denver School of Medicine, Denver, Colorado, USA.
Robert G McCormackUniversity of British Columbia/Fraser Health Authority, British Columbia, Canada.
Bruce S MillerUniversity of Michigan, Ann Arbor, Michigan, USA.
Carl W NissenConnecticut Children's Medical Center, Hartford, Connecticut, USA.
Daniel F O'NeillLittleton Regional Healthcare, Littleton, New Hampshire, USA.
Brett D OwensWarren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Richard D ParkerCleveland Clinic, Cleveland, Ohio, USA.
Mark L PurnellAspen Orthopedic Associates, Aspen, Colorado, USA.
Arun J RamappaBeth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Michael A RauhState University of New York at Buffalo, Buffalo, New York, USA.
Arthur C RettigMethodist Sports Medicine, Indianapolis, Indiana, USA.
Jon K SekiyaUniversity of Michigan, Ann Arbor, Michigan, USA.
Kevin G SheaIntermountain Orthopaedics, Boise, Idaho, USA.
Orrin H ShermanNYU Hospital for Joint Diseases, New York, New York, USA.
James R SlauterbeckUniversity of South Alabama, Mobile, Alabama, USA.
Matthew V SmithWashington University in St Louis, St Louis, Missouri, USA.
Jeffrey T SpangUniversity of North Carolina Medical Center, Chapel Hill, North Carolina, USA.
Ltc Steven J SvobodaKeller Army Community Hospital, United States Military Academy, West Point, New York, USA.
Timothy N TaftUniversity of North Carolina Medical Center, Chapel Hill, North Carolina, USA.
Joachim J TenutaAlbany Medical Center, Albany, New York, USA.
Edwin M TingstadInland Orthopaedic Surgery and Sports Medicine Clinic, Pullman, Washington, USA.
Armando F VidalUniversity of Colorado Denver School of Medicine, Denver, Colorado, USA.
Darius G ViskontasRoyal Columbian Hospital, New Westminster, British Columbia, Canada.
Richard A WhiteFitzgibbon's Hospital, Marshall, Missouri, USA.
James S WilliamsCleveland Clinic, Euclid, Ohio, USA.
Michelle L WolcottUniversity of Colorado Denver School of Medicine, Denver, Colorado, USA.
Brian R WolfUniversity of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
James J YorkOrthopaedic and Sports Medicine Center, LLC, Pasedena, Maryland, USA.
Cleveland Clinic · USUniversity of North Carolina at Chapel Hill · USVanderbilt University · USRush University Medical Center · USHospital for Special Surgery · USMayo Clinic · USWashington University in St. Louis · USUniversity of Michigan · USUniversity Orthopaedic Associates · USAmerican Sports Medicine Institute · USBeth Israel Deaconess Medical Center · USChildren's Hospital of Philadelphia · USIntermountain Healthcare · USRoyal Columbian Hospital · CASlocum Research and Education Foundation · USUniversity of British Columbia · CAUniversity of California, Los Angeles · USWestern University · CAAlbany Medical Center Hospital · USBridger Photonics (United States) · US

Funding

Revision ACL Reconstructions: A Comparative Effectiveness Treatment StudyR01AR060846 · NIAMS · WASHINGTON UNIVERSITY · PI WRIGHT, RICK W · 2011 to 2025
$6.7M
NIAMS NIH HHS R01 AR060846
6 · The paper itself

Abstract

backgroundMeniscal and chondral damage is common in the patient undergoing revision anterior cruciate ligament (ACL) reconstruction. PURPOSE: To determine if meniscal and/or articular cartilage pathology at the time of revision ACL surgery significantly influences a patient's outcome at 6-year follow-up. STUDY

designCohort study; Level of evidence, 3.

methodsPatients undergoing revision ACL reconstruction were prospectively enrolled between 2006 and 2011. Data collection included baseline demographics, surgical technique, pathology, treatment, and scores from 4 validated patient-reported outcome instruments: International Knee Documentation Committee (IKDC), Knee injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Marx Activity Rating Scale. Patients were followed up at 6 years and asked to complete the identical set of outcome instruments. Regression analysis assessed the meniscal and articular cartilage pathology risk factors for clinical outcomes 6 years after revision ACL reconstruction.

resultsAn overall 1234 patients were enrolled (716 males, 58%; median age, 26 years). Surgeons reported the pathology at the time of revision surgery in the medial meniscus (45%), lateral meniscus (36%), medial femoral condyle (43%), lateral femoral condyle (29%), medial tibial plateau (11%), lateral tibial plateau (17%), patella (30%), and trochlea (21%). Six-year follow-up was obtained on 79% of the sample (980/1234). Meniscal pathology and articular cartilage pathology (medial femoral condyle, lateral femoral condyle, lateral tibial plateau, trochlea, and patella) were significant drivers of poorer patient-reported outcomes at 6 years (IKDC, KOOS, WOMAC, and Marx). The most consistent factors driving outcomes were having a medial meniscal excision (either before or at the time of revision surgery) and patellofemoral articular cartilage pathology. Six-year Marx activity levels were negatively affected by having either a repair/excision of the medial meniscus (odds ratio range, 1.45-1.72;

conclusionMeniscal and chondral pathology at the time of revision ACL reconstruction has continued significant detrimental effects on patient-reported outcomes at 6 years after revision surgery.

Indexed as

Anterior Cruciate Ligament InjuriesCartilage, ArticularOsteoarthritisAdultCohort StudiesFollow-Up StudiesHumansMaleMenisci, Tibialanterior cruciate ligament (ACL)knee articular cartilagemeniscusoutcomesrevision ACL reconstruction

Identifiers

PMID36734487
PMCPMC10338044
OpenAlexW4319058176

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.