Trial reportAnaesthesiology intensive therapy2022
Femoral nerve blockade versus local infiltration analgesia for primary knee arthroplasty. Randomised controlled trial.
Trial report in Anaesthesiology intensive therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Continuous femoral nerve block as pain management following total knee arthroplasty: a systematic review.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Combined iPACK and adductor canal block versus two-level erector spinae plane block in elderly patients undergoing total knee arthroplasty: a randomized, triple-blinded clinical trial.Archives of orthopaedic and trauma surgery · 2026Trial
- Management of Postoperative Pain Following Primary Total Knee Arthroplasty: A Level I Evidence-Based Bayesian Network Meta-Analysis.Pharmaceuticals (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTotal knee arthroplasty (TKA) is associated with severe postoperative pain and significant chronification. The lengthy debate is on-going regarding the best balance between pain management, safety, and functional rehabilitation. MATERIAL AND
methodsFifty adult patients scheduled for primary unilateral TKA were randomly divided into 2 groups: continuous femoral nerve blockade (FNB; n = 25) and local infiltration analgesia (LIA; n = 25). We compared FNB and LIA in terms of function (primary outcome; number of steps, recorded using a step-tracking watch), pain scores using the visual analogue scale (VAS), opioid consumption (morphine equivalents), muscle strength (Janda Score), side effects, and complications until postoperative day 5. The results are presented as (mean ± SD).
resultsAfter excluding one patient, 49 were analysed (25 FNB, 24 LIA). There were no differences between the groups in the primary outcome. The VAS score (day 0: 23 ± 17.7 vs. 32.8 ± 21.5; P = 0.101; day 1: 31.0 ± 22.3 vs. 41.7 ± 25.3; P = 0.112) and mean opioid consumption (day 0: 0.39 ± 0.17 vs. 0.50 ± 0.38; P = 0.655; day 1: 0.60 ± 0.27 vs. 0.71 ± 0.38; P = 0.406) did not differ significantly between the groups. Muscle strength was significantly lower in the FNB group on days 0 (3.05 ± 1.67 vs. 4.35 ± 0.91; P = 0.009) and 1 (2.71 ± 1.57 vs. 3.67 ± 1.18; P = 0.030). Side effects and complications had a similarly low incidence in both groups, and except for constipation (FNB < LIA) no difference was seen.
conclusionsBased on the results of this study, both FNB and LIA are associated with similar outcomes, and one cannot be recommended over the other.
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