Observational study in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
19 authors at 5 institutions in 1 country.
Tim Bastian BraemswigKlinik und Hochschulambulanz für Neurologie Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0001-6112-2800
Madeleine KusserowKlinik für Innere Medizin Bundeswehrkrankenhaus Berlin Berlin Germany.
Frederik BeckhoffDepartment of Cardiology Campus Benjamin Franklin Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0002-3609-4366
Markus ReinthalerDepartment of Cardiology Campus Benjamin Franklin Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.
Regina von RennenbergKlinik und Hochschulambulanz für Neurologie Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0003-3444-2045
Hebun ErdurKlinik und Hochschulambulanz für Neurologie Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0001-5383-9625
Jan F ScheitzKlinik und Hochschulambulanz für Neurologie Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0001-5835-4627
Ivana GalinovicCenter for Stroke Research Berlin (CSB) Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0003-4904-8251
Kersten VillringerCenter for Stroke Research Berlin (CSB) Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0003-4192-9193
David M LeistnerBerlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin Berlin Germany.ORCID 0000-0002-4351-420X
Heinrich J AudebertKlinik und Hochschulambulanz für Neurologie Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0002-4785-0366
Matthias EndresKlinik und Hochschulambulanz für Neurologie Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0001-6520-3720
Ulf LandmesserBerlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin Berlin Germany.ORCID 0000-0002-0214-3203
Karl Georg HaeuslerDepartment of Neurology Universitätsklinikum Würzburg Würzburg Germany.ORCID 0000-0002-6389-5054
Jochen B FiebachCenter for Stroke Research Berlin (CSB) Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0002-7936-6958
Alexander LautenDepartment of Cardiology Campus Benjamin Franklin Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.
Andreas RilligDepartment of Cardiology Campus Benjamin Franklin Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0003-3457-0936
Christian H NolteKlinik und Hochschulambulanz für Neurologie Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.ORCID 0000-0001-5577-1775
Humboldt-Universität zu Berlin · DEGerman Center for Neurodegenerative Diseases · DEEppendorf (Germany) · DEGoethe University Frankfurt · DEUniversitätsklinikum Würzburg · DE
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Background Cerebral microbleeds (CMBs) are increasingly recognized as "covert" brain lesions indicating increased risk of future neurological events. However, data on CMBs in patients undergoing catheter-based structural heart interventions are scarce. Therefore, we assessed occurrence and predictors of new CMBs in patients undergoing catheter-based left atrial appendage closure and percutaneous mitral valve repair using the MitraClip System. Methods and Results We conducted an exploratory analysis using data derived from 2 prospective, observational studies. Eligible patients underwent cerebral magnetic resonance imaging (3 Tesla) examinations and cognitive tests (using the Montreal Cognitive Assessment) before and after catheter-based left atrial appendage closure and percutaneous mitral valve repair. Forty-seven patients (53% men; median age, 77 years) were included. New CMBs occurred in 17 of 47 patients (36%) following catheter-based structural heart interventions. Occurrences of new CMBs did not differ significantly between patients undergoing catheter-based left atrial appendage closure and percutaneous mitral valve repair (7/25 versus 10/22;
Indexed as
Cardiac Surgical ProceduresMitral Valve InsufficiencyAgedCathetersCerebral HemorrhageFemaleHumansMagnetic Resonance ImagingMaleProspective StudiesTreatment Outcomecatheter‐based structural heart interventionscerebral microbleedsleft atrial appendage closuremitral valve repair (MVR) using the MitraClip System
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
New Cerebral Microbleeds After Catheter-Based Structural Heart Interventions: An Exploratory Analysis. · full record | OpenQuestion