Evidence map›Paper›PMID 36734339›Full record

ArticleJournal of the American Heart Association2023

Long-Term Changes in Estimated Glomerular Filtration Rate in Left Ventricular Assist Device Recipients: A Longitudinal Joint Model Analysis.

Bethany Roehm, Susan Hedayati, Amanda R Vest, Gaurav Gulati, Jonathan Miao, Hocine Tighiouart, Daniel E Weiner, Lesley A Inker

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Kidney health and function with left ventricular assist devices.Current opinion in nephrology and hypertension · 2023
    Review
  4. Left Ventricular Assist Devices and Renal Ramifications.Journal of the American Heart Association · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bethany RoehmDivision of Nephrology University of Texas Southwestern Medical Center Dallas TX.ORCID 0000-0002-8046-4651
Susan HedayatiDivision of Nephrology University of Texas Southwestern Medical Center Dallas TX.ORCID 0000-0001-8850-4729
Amanda R VestDivision of Cardiology Tufts Medical Center Boston MA.ORCID 0000-0001-8274-5660
Gaurav GulatiDivision of Cardiology Tufts Medical Center Boston MA.ORCID 0000-0002-7701-0878
Jonathan MiaoDivision of Nephrology Tufts Medical Center Boston MA.
Hocine TighiouartTufts Medical Center Institute for Clinical Research and Health Policy Studies Boston MA.ORCID 0000-0003-1448-327X
Daniel E WeinerDivision of Nephrology Tufts Medical Center Boston MA.ORCID 0000-0002-8775-394X
Lesley A InkerDivision of Nephrology Tufts Medical Center Boston MA.ORCID 0000-0003-2820-9482
Tufts Medical Center · USThe University of Texas Southwestern Medical Center · USTufts University · US

Funding

Epidemiology, Clinical Trials and Outcomes Research In NephrologyT32DK007777 · NIDDK · TUFTS MEDICAL CENTER · PI SARNAK, MARK J · 1999 to 2020
$4.1M
NIDDK NIH HHS T32 DK007777
6 · The paper itself

Abstract

Background Advanced kidney disease is often a relative contraindication to left ventricular assist device (LVAD) implantation because of concerns for poor outcomes including worsening kidney disease. Data are lacking on long-term changes and sex-based differences in estimated glomerular filtration rate (eGFR), with published data limited by potential bias introduced by the competing risks of death and heart transplantation. Methods and Results We conducted a longitudinal analysis of 288 adults receiving durable continuous-flow LVADs from January 2010 to December 2017 at a single center. A joint model was constructed to evaluate change in eGFR over 2 years, the prespecified primary outcome, adjusted for the competing risks of death and heart transplantation. Median baseline eGFR was 60 mL/min per 1.73 m

Indexed as

Heart-Assist DevicesHeart FailureHeart TransplantationKidney DiseasesAdultFemaleGlomerular Filtration RateHumansMaleRetrospective Studiescompeting riskeGFRjoint modelLVADventricular assist device

Identifiers

PMID36734339
PMCPMC9973635
OpenAlexW4319058214

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.