Evidence map›Paper›PMID 36734236›Full record

ArticleDevelopment and psychopathology2024

Risk and resilience factors for psychopathology during pregnancy: An application of the Hierarchical Taxonomy of Psychopathology (HiTOP).

Hannah M Clark, Benjamin L Hankin, Angela J Narayan, Elysia Poggi Davis

Abstract read
In one paragraph

Article in Development and psychopathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Parents' Positive Childhood Experiences: A Scoping Review.Adversity and resilience science · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hannah M ClarkDepartment of Psychology, Brandeis University, 415 South St., Waltham, MA, 02453, USA.ORCID 0000-0002-5946-6521
Benjamin L HankinDepartment of Psychology, University of Illinois at Urbana-Champaign, 603 East Daniel St., Champaign, IL, 61820, USA.
Angela J NarayanDepartment of Psychology, University of Denver, 2155 South Race St., Denver, CO, 80208, USA.ORCID 0000-0002-9019-8377
Elysia Poggi DavisDepartment of Psychology, University of Denver, 2155 South Race St., Denver, CO, 80208, USA.ORCID 0000-0001-6345-9271

Funding

Reducing Fetal Exposure to Maternal Depression to Improve Infant Risk MechanismsR01MH109662 · NIMH · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI DAVIS, ELYSIA POGGI, HANKIN, BENJAMIN L · 2017 to 2021
$4.0M
Reducing maternal prenatal depression to improve child cardiovascular healthR01HL155744 · NHLBI · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI DAVIS, ELYSIA POGGI, DOOM, JENALEE RAE · 2021 to 2025
$3.6M
NHLBI NIH HHS R01 HL155744NIMH NIH HHS R01 MH109662
6 · The paper itself

Abstract

Pregnancy is a time of increased vulnerability to psychopathology, yet limited work has investigated the extent to which variation in psychopathology during pregnancy is shared and unshared across syndromes and symptoms. Understanding the structure of psychopathology during pregnancy, including associations with childhood experiences, may elucidate risk and resilience factors that are transdiagnostic and/or specific to particular psychopathology phenotypes. Participants were 292 pregnant individuals assessed using multiple measures of psychopathology. Confirmatory factor analyses found evidence for a structure of psychopathology consistent with the Hierarchical Taxonomy of Psychopathology (HiTOP). A common transdiagnostic factor accounted for most variation in psychopathology, and both adverse and benevolent childhood experiences (ACEs and BCEs) were associated with this transdiagnostic factor. Furthermore, pregnancy-specific anxiety symptoms most closely reflected the dimension of Fear, which may suggest shared variation with manifestations of fear that are not pregnancy-specific. ACEs and BCEs also linked to specific prenatal psychopathology involving thought problems, detachment, and internalizing, externalizing, antagonistic, and antisocial behavior. These findings extend the dimensional and hierarchical HiTOP model to pregnant individuals and show how maternal childhood risk and resilience factors relate to common and specific forms of psychopathology during pregnancy as a period of enhanced vulnerability.

Indexed as

Mental DisordersPregnancyPregnancy ComplicationsAdultAdverse Childhood ExperiencesAntisocial Personality DisorderDisease SusceptibilityFemaleGestational AgeHumansPhenotypePsychopathologyResilience, PsychologicalYoung Adultadverse childhood experiences (ACEs)benevolent childhood experiences (BCEs)Hierarchical Taxonomy of Psychopathology (HiTOP)pregnancyresilience

Identifiers

PMID36734236
PMCPMC10397364

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.