Evidence map›Paper›PMID 36734234›Full record

ArticleStroke2023

Rehabilitation Therapy Doses Are Low After Stroke and Predicted by Clinical Factors.

Brittany M Young, E Alison Holman, Steven C Cramer, STRONG Study Investigators

Open access · greenAbstract read
In one paragraph

Article in Stroke, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Brittany M YoungDepartment of Neurology, University of California, Los Angeles (B.M.Y., S.C.C.).ORCID 0000-0002-8925-1417
E Alison HolmanSue and Bill Gross School of Nursing, University of California, Irvine (E.A.H.).ORCID 0000-0001-5076-8403
Steven C CramerDepartment of Neurology, University of California, Los Angeles (B.M.Y., S.C.C.).ORCID 0000-0002-6214-6211
STRONG Study Investigators
University of California, Los Angeles · USUniversity of California, Irvine · US

Funding

Genetic variation, stress, and functional outcomes after stroke rehabilitationR01NR015591 · NINR · UNIVERSITY OF CALIFORNIA-IRVINE · PI CRAMER, STEVEN C., HOLMAN, ELLEN ALISON · 2015 to 2020
$2.6M
RR&D Research Career Scientist Award ApplicationIK6RX003543 · VA · VA NORTHERN CALIFORNIA HEALTH CARE SYS · PI PATTEN, CAROLYNN · 2020 to 2025
–
NINR NIH HHS R01 NR015591RRD VA IK6 RX003543
6 · The paper itself

Abstract

backgroundStroke is a leading cause of long-term disability. Greater rehabilitation therapy after stroke is known to improve functional outcomes. This study examined therapy doses during the first year of stroke recovery and identified factors that predict rehabilitation therapy dose.

methodsAdults with new radiologically confirmed stroke were enrolled 2 to 10 days after stroke onset at 28 acute care hospitals across the United States. Following an initial assessment during acute hospitalization, the number of physical therapy, occupational therapy, and speech therapy sessions were determined at visits occurring 3, 6, and 12 months following stroke. Negative binomial regression examined whether clinical and demographic factors were associated with therapy counts. False discovery rate was used to correct for multiple comparisons.

resultsOf 763 patients enrolled during acute stroke admission, 510 were available for follow-up. Therapy counts were low overall, with most therapy delivered within the first 3 months; 35.0% of patients received no physical therapy; 48.8%, no occupational therapy, and 61.7%, no speech therapy. Discharge destination was significantly related to cumulative therapy; the percentage of patients discharged to an inpatient rehabilitation facility varied across sites, from 0% to 71%. Most demographic factors did not predict therapy dose, although Hispanic patients received a lower cumulative amount of physical therapy and occupational therapy. Acutely, the severity of clinical factors (grip strength and National Institutes of Health Stroke Scale score, as well as National Institutes of Health Stroke Scale subscores for aphasia and neglect) predicted higher subsequent therapy doses. Measures of impairment and function (Fugl-Meyer, modified Rankin Scale, and Stroke Impact Scale Activities of Daily Living) assessed 3 months after stroke also predicted subsequent cumulative therapy doses.

conclusionsRehabilitative therapy doses during the first year poststroke are low in the United States. This is the first US-wide study to demonstrate that behavioral deficits predict therapy dose, with patients having more severe deficits receiving higher doses. Findings suggest directions for identifying groups at risk of receiving disproportionately low rehabilitation doses.

Indexed as

AphasiaOccupational TherapyStrokeStroke RehabilitationActivities of Daily LivingAdultHumansRecovery of FunctionUnited StatesaphasiademographyrehabilitationstrokeUnited States

Identifiers

PMID36734234
PMCPMC9992003
OpenAlexW4319063423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.