Evidence map›Paper›PMID 36734018›Full record

ArticleDrug and alcohol review2023

Cannabis use and gastrointestinal tract illnesses: The National Health and Nutrition Examination Surveys, 2005-2018.

Alyssa Vanderziel, Omayma Alshaarawy

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Cannabis-Induced Gastrointestinal Tract Symptoms in the Adult Population: A Systematic Review.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alyssa VanderzielDepartment of Family Medicine, College of Human Medicine, Michigan State University, East Lansing, USA.ORCID 0000-0003-0971-1485
Omayma AlshaarawyDepartment of Family Medicine, College of Human Medicine, Michigan State University, East Lansing, USA.ORCID 0000-0002-5968-0245
Michigan State University · US

Funding

Using pre-clinical biomarkers and epidemiological models to assess the effects of cannabinoids on diseaseR00AT009156 · NCCIH · MICHIGAN STATE UNIVERSITY · PI ALSHAARAWY, OMAYMA O · 2018 to 2020
$744k
Using pre-clinical biomarkers and epidemiological models to assess the effects of cannabinoids on diseaseK99AT009156 · NCCIH · MICHIGAN STATE UNIVERSITY · PI ALSHAARAWY, OMAYMA O · 2016 to 2017
$181k
Cannabis legalization and use during pregnancy: A Michigan StudyR36DA054487 · NIDA · MICHIGAN STATE UNIVERSITY · PI VANDERZIEL, ALYSSA · 2021 to 2021
$54k
NCCIH NIH HHS K99 AT009156NCCIH NIH HHS R00 AT009156NIDA NIH HHS R36 DA054487
6 · The paper itself

Abstract

introductionThe antiemetic properties of cannabis have motivated its use in the management of chemotherapy-induced nausea and vomiting. Conversely, case reports of intractable vomiting among heavy cannabis users have increasingly appeared in the literature. Studies on cannabis and gastrointestinal tract (GIT) health are scare. Here, we use data for the National Health and Nutrition Examination Surveys (NHANES, 2005-2018) to estimate the association between cannabis use and GIT illness.

methodsThe study sample included non-pregnant adult NHANES participants (20-59 years) without history of cancer or HIV (n = 18,753). Cannabis use was categorised into never, former (0 day in the past 30 days), infrequent (1-2 days), occasional (3-19 days) and frequent (20-30 days) use. Recent GIT illness was defined as experiencing GIT illness with vomiting or diarrhoea that started in the 30 days prior to NHANES. Logistic regression was used to regress GIT illness on cannabis use, adjusting for potential confounders.

resultsCompared to never use, frequent cannabis use was associated with higher odds of GIT illness (OR = 1.4; 95% confidence interval 1.04, 1.9). There were no associations between former, infrequent or occasional cannabis use and GIT illness. DISCUSSION AND

conclusionsFrequent cannabis use is associated with GIT illnesses in a large cross-sectional study of US residents. It is possible that frequent cannabis use adversely affects GIT health, consistent with clinical case reports. Alternatively, patients with GIT illness might self-medicate with cannabis given its antiemetic properties. Prospective studies are needed to understand the effects of cannabis use on GIT health.

Indexed as

AntiemeticsCannabisHallucinogensAdultCross-Sectional StudiesGastrointestinal TractHumansNutrition SurveysVomitingAntiemeticsHallucinogenscannabisemesisGITNHANES

Identifiers

PMID36734018
PMCPMC10192003
OpenAlexW4319062766

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.