Evidence map›Paper›PMID 36733941›Full record

ArticleFrontiers in genetics2022

Identification of a dysfunctional exon-skipping splice variant in

Yu Toyoda, Sung Kweon Cho, Velibor Tasic, Kateřina Pavelcová, Jana Bohatá, Hiroshi Suzuki, Victor A David, Jaeho Yoon, Anna Pallaiova, Jana Šaligová and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. NewGenes · 2023
    Article
  8. Pathogenic Variants ofInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 6 countries.

Yu ToyodaDepartment of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
Sung Kweon ChoMolecular Genetics Epidemiology Section, Basic Research Laboratory, National Cancer Institute and Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Velibor TasicFaculty of Medicine, University Ss. Cyril and Methodius, Skopje, North Macedonia.
Kateřina PavelcováInstitute of Rheumatology, Prague, Czechia.
Jana BohatáInstitute of Rheumatology, Prague, Czechia.
Hiroshi SuzukiDepartment of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
Victor A DavidDepartment of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
Jaeho YoonCancer and Developmental Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, United States.
Anna PallaiovaNephro Dialysis Center, Michalovce, Slovakia.
Jana ŠaligováMetabolic Clinic, Children's Faculty Hospital, Košice, Slovakia.
Darryl NousomeCCR Collaborative Bioinformatics Resource, Center for Cancer Research, National Cancer Institute, Frederick, MD, United States.
Raul CachauIntegrated Data Science Section, Research Technologies Branch, National Institute of Allergies and Infectious Diseases, Bethesda, MD, United States.
Cheryl A WinklerMolecular Genetics Epidemiology Section, Basic Research Laboratory, National Cancer Institute and Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Tappei TakadaDepartment of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
Blanka StibůrkováInstitute of Rheumatology, Prague, Czechia.
University of Tokyo Hospital · JPInstitute of Rheumatology · CZNational Cancer Institute · USAjou University · KRSaints Cyril and Methodius University of Skopje · MKUniversity Hospital Bratislava · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal hypouricemia (RHUC) is a pathological condition characterized by extremely low serum urate and overexcretion of urate in the kidney; this inheritable disorder is classified into type 1 and type 2 based on causative genes encoding physiologically-important urate transporters,

Indexed as

genetic disorderrenal urate handlingRHUCsplicing varianturate

Identifiers

PMID36733941
PMCPMC9887137
OpenAlexW4316668841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.