ArticleFrontiers in endocrinology2022
Incidence and long-term specific mortality trends of metabolic syndrome in the United States.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Trial
- Budget impact of xanomeline and trospium chloride for the treatment of adults with schizophrenia in the United States.Journal of managed care & specialty pharmacy · 2026Article
- Modulation of Sirtuin-1 by Resveratrol as a Potential Therapy in Alleviating Metabolic Syndrome.Cell biochemistry and biophysics · 2026Review
- Effects of age and sex on all-cause mortality among NHANES participants with metabolic syndrome and rheumatoid arthritis.BMC cardiovascular disorders · 2026Article
- Article
- The Predictive Ability and Trend of Continuous Metabolic Syndrome (cMets) Score as a Marker for the Presence of Metabolic Syndrome among Iranian Adults from 2007 to 2025 Using STEPS Studies.International journal of preventive medicine · 2026Article
- Association between serum 25(OH)D, oxidative balance score, and mortality among individuals with metabolic syndrome: a cohort study.Diabetology & metabolic syndrome · 2025Article
- Article
- Association of C-reactive protein to albumin ratio with prevalence and mortality in metabolic syndrome: NHANES 1999-2010.European journal of medical research · 2025Article
- Review
- Prevalence of the Metabolic Syndrome and its Associated Factors among Hospital Workers at a Rwandan Provincial Hospital: A Cross-Sectional Study.Rwanda journal of medicine and health sciences · 2025Article
- Evaluating the association between TSH and FT4 levels and the incidence of metabolic syndrome: insights from the Tehran thyroid study using joint modeling.Scientific reports · 2025Article
- Microbiome in heritage: how maternal microbiome transmission impacts next generation health.Microbiome · 2025Review
- UK Biobank study of the association between circadian syndrome and cardio-kidney events or all-cause mortality.Communications medicine · 2025Article
- The association between metabolic syndrome severity and frailty risk in patients with rheumatoid arthritis: a cross-sectional study.Arthritis research & therapy · 2025Article
- Prevalence, Disparities, and Mortality of Cardiovascular-Kidney-Metabolic Syndrome in US Adults, 2011-2018.The American journal of medicine · 2025Article
- Relationship between atherosclerotic burden and sarcopenia in U.S. adults: A cross-sectional study based on the NHANES database.Scientific reports · 2025Article
- Mechanisms of Flame Retardant Toxicity and Their Impacts on Anxiety and Cognition in the Brain.Endocrinology · 2025Review
- MicroRNAs as Epigenetic Biomarkers of Pathogenetic Mechanisms of the Metabolic Syndrome Induced by Antiseizure Medications: Systematic Review.Journal of clinical medicine · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Metabolic syndrome (MetS) is extremely prevalent and related to severe diseases and death. This study aims to investigate the incidence and mortality trends among MetS over the past few decades. The gender and age differences of MetS are also explored. Patients and methods: Adults with MetS were screened in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2014. The mortality data were also acquired. Then we assessed the incidence and mortality trends of MetS in the United States. Results: Our study included 14171 participants with a mean age of 46.8 ± 19.3 years, of whom 7354 (51.9%) were women. Among them, 4789 participants were subsequently diagnosed with MetS. From 1999 to 2014, the overall trend of MetS incidence increased (from 27.6 to 32.3%; adjusted odds ratios [aOR], 1.71; 95% confidence interval [CI], 1.42-2.05; Conclusion: From 1999 to 2014, the incidence of MetS in U.S. adults significantly increased overall, while the mortality rate of MetS had a considerable downward trend. Both trends showed marked gender differences, being more prevalent and at lower risk in women compared with men. It is important to identify the factors that will curb the incidence of MetS and decrease mortality, especially in male patients.
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