Evidence map›Paper›PMID 36733798›Full record

ArticleFrontiers in endocrinology2022

Changes in and the association of retinal blood perfusion and retinal nerves in diabetic patients without retinopathy.

Jianchen Hao, Jiantong Du, Xiaopeng Gu, Yadi Zhang, Liu Yang, Shijie Zhang

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jianchen HaoDepartment of Ophthalmology, Peking University First Hospital, Beijing, China.
Jiantong DuDepartment of Ophthalmology, Peking University First Hospital, Beijing, China.
Xiaopeng GuDepartment of Ophthalmology, Peking University First Hospital, Beijing, China.
Yadi ZhangDepartment of Ophthalmology, Peking University First Hospital, Beijing, China.
Liu YangDepartment of Ophthalmology, Peking University First Hospital, Beijing, China.
Shijie ZhangDepartment of Ophthalmology, Peking University First Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore intraretinal blood flow perfusion and nerve changes, as well as the correlation between them, in diabetic patients without diabetic retinopathy (NDR). Method: Eighty-six NDR patients (86 eyes) who attended the ophthalmology clinic between December 2019 and December 2021 were included. Sixty-four eyes of 64 healthy examined controls in the same period were selected as the control group. The patients underwent routine ophthalmological examination, optical coherence tomography (OCT) and OCT angiography. Results: The average thickness, minimum thickness and thickness of each quadrant except for the superior temporal quadrant of the ganglion cell-inner plexiform layer (GCIPL) in the macular area of the affected eyes in the NDR group were lower than that of the tested eyes in the control group ( Conclusion: In diabetic patients without diabetic retinopathy, the superficial retinal vessel density in the macular area positively correlated with GCIPL thickness, and the superficial retinal vessel density around the optic disc was not correlated with RNFL thickness.

Indexed as

Diabetes MellitusDiabetic RetinopathyRetinal DiseasesHumansNerve FibersRetinaRetinal Ganglion CellsTomography, Optical Coherencediabetic retinopathyganglion cell-inner plexiform layerGCIPL thicknessintraretinal blood flow perfusionRNFL thickness

Identifiers

PMID36733798
PMCPMC9887038

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.