Evidence map›Paper›PMID 36733754›Full record

ArticleBiomedical optics express2022

Retinal imaging using adaptive optics optical coherence tomography with fast and accurate real-time tracking.

Sanam Mozaffari, Fabio Feroldi, Francesco LaRocca, Pavan Tiruveedhula, Patrick D Gregory, B Hyle Park, Austin Roorda

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Biomedical optics express · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sanam MozaffariHerbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley, CA 94720, USA.
Fabio FeroldiHerbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID https://orcid.org/0000-0002-3815-5329
Francesco LaRoccaHerbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley, CA 94720, USA.
Pavan TiruveedhulaHerbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley, CA 94720, USA.
Patrick D GregoryDepartment of Bioengineering, University of California, Riverside, CA 92521, USA.
B Hyle ParkDepartment of Bioengineering, University of California, Riverside, CA 92521, USA.
Austin RoordaHerbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley, CA 94720, USA.
University of California, Berkeley · USUniversity of California, Riverside · US

Funding

UC Berkeley Vision Science COREP30EY003176 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI RICHARD H KRAMER · 1985 to 2026
$16.4M
TRAINING PROGRAM IN VISION SCIENCET32EY007043 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Suzanne MJ FLEISZIG · 1985 to 2026
$12.9M
Advanced Technology to Study Visual Function on a Cellular ScaleR01EY023591 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI DUNCAN, JACQUE LYNNE, ROORDA, AUSTIN · 2014 to 2023
$11.2M
Optoretinography: All-optical measures of functional activity in the human retinaU01EY032055 · NEI · UNIVERSITY OF WASHINGTON · PI PALANKER, DANIEL V, ROORDA, AUSTIN · 2021 to 2025
$5.2M
Interferometric Optophysiology of the Human RetinaU01EY025501 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROORDA, AUSTIN · 2015 to 2019
$3.4M
NEI NIH HHS P30 EY003176NEI NIH HHS R01 EY023591NEI NIH HHS T32 EY007043NEI NIH HHS U01 EY025501NEI NIH HHS U01 EY032055
6 · The paper itself

Abstract

One of the main obstacles in high-resolution 3-D retinal imaging is eye motion, which causes blur and distortion artifacts that require extensive post-processing to be corrected. Here, an adaptive optics optical coherence tomography (AOOCT) system with real-time active eye motion correction is presented. Correction of ocular aberrations and of retinal motion is provided by an adaptive optics scanning laser ophthalmoscope (AOSLO) that is optically and electronically combined with the AOOCT system. We describe the system design and quantify its performance. The AOOCT system features an independent focus adjustment that allows focusing on different retinal layers while maintaining the AOSLO focus on the photoreceptor mosaic for high fidelity active motion correction. The use of a high-quality reference frame for eye tracking increases revisitation accuracy between successive imaging sessions, allowing to collect several volumes from the same area. This system enables spatially targeted retinal imaging as well as volume averaging over multiple imaging sessions with minimal correction of motion in post processing.

Identifiers

PMID36733754
PMCPMC9872892
OpenAlexW4302284234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.