Evidence map›Paper›PMID 36733251›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2023

Genome editing with natural and engineered CjCas9 orthologs.

Siqi Gao, Yao Wang, Tao Qi, Jingjing Wei, Ziying Hu, Jingtong Liu, Shuna Sun, Huihui Liu, Yongming Wang

Open access · greenAbstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. In vivo genome editing with a novel Cj4Cas9.Communications biology · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Engineering of SauriCas9 with enhanced specificity.Molecular therapy. Nucleic acids · 2025
    Article
  8. Article
  9. Article
  10. Characterization of NiCas12b for In Vivo Genome Editing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Siqi GaoState Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai 200438, China.
Yao WangState Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai 200438, China.
Tao QiState Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai 200438, China.
Jingjing WeiState Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai 200438, China.
Ziying HuState Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai 200438, China.
Jingtong LiuState Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai 200438, China.
Shuna SunChildren's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China. Electronic address: sun_shuna@fudan.edu.cn.
Huihui LiuExperimental Center of Forestry in North China, Chinese Academy of Forestry, Beijing 102300, China. Electronic address: liuhuihui800@caf.ac.cn.
Yongming WangState Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai 200438, China. Electronic address: ymw@fudan.edu.cn.
Fudan University · CNChinese Academy of Forestry · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CjCas9 is one of the smallest CRISPR-associated (Cas9) nucleases for mammalian genome editing. However, it requires a long N

Indexed as

CRISPR-Cas SystemsGene EditingAnimalsDNAGenomeMammalsMutationSwineDNAchimeric Cas9CjCas9compact Cas9Compact Cas9CRISPR/Cas9high-fidelityHsp1-Hsp2Cas9

Identifiers

PMID36733251
PMCPMC10124074
OpenAlexW4318831418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.