Evidence map›Paper›PMID 36732799›Full record

ArticleBMC pregnancy and childbirth2023

Breastfeeding difficulties in the first 6 weeks postpartum among mothers with chronic conditions: a latent class analysis.

Natalie V Scime, Amy Metcalfe, Alberto Nettel-Aguirre, Kara Nerenberg, Cynthia H Seow, Suzanne C Tough, Kathleen H Chaput

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. LATCH score and 6-month exclusive breastfeeding in a Baby-Friendly Hospital.Revista da Associacao Medica Brasileira (1992) · 2026
    Observational
  2. Article
  3. Article
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  5. Article
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  8. Topical review: Lactation and use of DMTs in women with MS.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Natalie V ScimeDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada. natalie.scime@ucalgary.ca.
Amy MetcalfeDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Alberto Nettel-AguirreCentre For Health and Social Analytics, School of Mathematics and Statistics, National Institute for Applied Statistical Research, University of Wollongong, Wollongong, NSW, Australia.
Kara NerenbergDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Cynthia H SeowDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Suzanne C ToughDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Kathleen H ChaputDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
University of Calgary · CA

Funding

CIHR Canada Graduate Scholarship Doctoral Award
6 · The paper itself

Abstract

backgroundBreastfeeding difficulties frequently exacerbate one another and are common reasons for curtailed breastfeeding. Women with chronic conditions are at high risk of early breastfeeding cessation, yet limited evidence exists on the breastfeeding difficulties that co-occur in these mothers. The objective of this study was to explore clusters of breastfeeding difficulties experienced up to 6 weeks postpartum among mothers with chronic conditions and to examine associations between chronic condition types and breastfeeding difficulty clusters.

methodsWe analyzed 348 mothers with chronic conditions enrolled in a prospective, community-based pregnancy cohort study from Alberta, Canada. Data were collected through self-report questionnaires. We used latent class analysis to identify clusters of early breastfeeding difficulties and multinomial logistic regression to examine whether types of chronic conditions were associated with these clusters, adjusting for maternal and obstetric factors.

resultsWe identified three clusters of breastfeeding difficulties. The "physiologically expected" cluster (51.1% of women) was characterized by leaking breasts and engorgement (reference outcome group); the "low milk production" cluster (15.4%) was discerned by low milk supply and infant weight concerns; and the "ineffective latch" cluster (33.5%) involved latch problems, sore nipples, and difficulty with positioning. Endocrine (adjusted relative risk ratio [RRR] 2.34, 95% CI 1.10-5.00), cardiovascular (adjusted RRR 2.75, 95% CI 1.01-7.81), and gastrointestinal (adjusted RRR 2.51, 95% CI 1.11-5.69) conditions were associated with the low milk production cluster, and gastrointestinal (adjusted RRR 2.44, 95% CI 1.25-4.77) conditions were additionally associated with the ineffective latch cluster.

conclusionHalf of women with chronic conditions experienced clusters of breastfeeding difficulties corresponding either to low milk production or to ineffective latch in the first 6 weeks postpartum. Associations with chronic condition types suggest that connections between lactation physiology and disease pathophysiology should be considered when providing breastfeeding support.

Indexed as

Breast FeedingMothersAlbertaCohort StudiesFemaleHumansInfantLatent Class AnalysisPostpartum PeriodPregnancyProspective StudiesBreast feedingChronic diseasePostpartum periodProspective studies

Identifiers

PMID36732799
PMCPMC9893695
OpenAlexW4319018763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.