Evidence map›Paper›PMID 36732739›Full record

ArticleBMC oral health2023

A time-dependent subdistribution hazard model for major dental treatment events in cancer patients: a nationwide cohort study.

Areum Han, Eun-Gee Park, Jeong-Hwa Yoon, Ji-Yeob Choi, Hee-Kyung Park, Seokyung Hahn

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Areum HanInterdisciplinary Program of Medical Informatics, Seoul National University College of Medicine, Seoul, Korea.
Eun-Gee ParkInterdisciplinary Program of Medical Informatics, Seoul National University College of Medicine, Seoul, Korea.
Jeong-Hwa YoonInstitute of Health Policy and Management, Medical Research Center, Seoul National University, Seoul, Korea.
Ji-Yeob ChoiDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.
Hee-Kyung ParkDepartment of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University, 101 Daehak-ro, Jongro-gu, Seoul, 03080, Korea. dentopark@snu.ac.kr.
Seokyung HahnInstitute of Health Policy and Management, Medical Research Center, Seoul National University, Seoul, Korea. hahns@snu.ac.kr.
Seoul National University · KRNational University College · PRSeoul National University Hospital · KR

Funding

Ministry of Health & Welfare, Republic of Korea HI19C1178National Research Foundation of Korea, South Korea 2022R1A2C101043711
6 · The paper itself

Abstract

backgroundDental care in cancer patients tends to be less prioritized. However, limited research has focused on major dental treatment events in cancer patients after the diagnosis. This study aimed to examine dental treatment delays in cancer patients compared to the general population using a national claims database in South Korea.

methodThe Korea National Health Insurance Service-National Sample Cohort version 2.0, collected from 2002 to 2015, was analyzed. Treatment events were considered for stomatitis, tooth loss, dental caries/pulp disease, and gingivitis/periodontal disease. For each considered event, time-dependent hazard ratios and associated 95% confidence intervals were calculated by applying a subdistribution hazard model with time-varying covariates. Mortality was treated as a competing event. Subgroup analyses were conducted by type of cancer.

resultsThe time-dependent subdistribution hazard ratios (SHRs) of stomatitis treatment were greater than 1 in cancer patients in all time intervals, 2.04 within 30 days after cancer diagnosis, and gradually decreased to 1.15 after 5 years. The SHR for tooth loss was less than 0.70 within 3 months after cancer diagnosis and increased to 1 after 5 years. The trends in SHRs of treatment events for other dental diseases were similar to those observed for tooth loss. Subgroup analyses by cancer type suggested that probability of all dental treatment event occurrence was higher in head and neck cancer patients, particularly in the early phase after cancer diagnosis.

conclusionApart from treatments that are associated with cancer therapy, dental treatments in cancer patients are generally delayed and cancer patients tend to refrain from dental treatments. Consideration should be given to seeking more active and effective means for oral health promotion in cancer patients.

Indexed as

Dental CariesNeoplasmsStomatitisTooth LossCohort StudiesDental CareHumansProportional Hazards ModelsCancer patientsCohort analysisCompeting risk analysisDental insuranceDental treatment delayHealth insuranceTime-dependent

Identifiers

PMID36732739
PMCPMC9896767
OpenAlexW4318982557

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.