Evidence map›Paper›PMID 36732724›Full record

ArticleBMC oral health2023

Does mandibular advancement with clear aligners have the same skeletal and dentoalveolar effects as traditional functional appliances?

Yanqi Wu, Qian Yu, Yunhui Xia, Bo Wang, Siyue Chen, Kaijun Gu, Bojun Zhang, Min Zhu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07608406 (Evaluation of the Efficacy of Functional Therapy Using Modified Twin Block Versus Clear Twin Block in Class II Skeletal Patients), which is not on this map. Cited by 28 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 5 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07608406 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of the Efficacy of Functional Therapy Using Modified Twin Block Versus Clear Twin Block in Class II Skeletal Patients: A Randomized Controlled Clinical Trial

TypeinterventionalSponsorUniversity of AleppoRan2026 to 2026Enrolled40ConditionsSkeletal Class II MalocclusionArmsModified Twin Block Appliance, Conventional Clear Twin Block Appliance
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Coefficient of efficiency and effectiveness of functional appliances in class II malocclusion treatment : A systematic review.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yanqi Wu *Department of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Qian Yu *Department of Pediatric Dentistry, Shanghai Xuhui District Dental Center, Shanghai, 200032, China.
Yunhui XiaDepartment of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Bo WangDepartment of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Siyue ChenDepartment of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Kaijun GuDepartment of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Bojun ZhangDepartment of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Min ZhuDepartment of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China. zminnie@126.com.
Shanghai Jiao Tong University · CNShanghai Ninth People's Hospital · CNShanghai Xuhui Central Hospital · CN

Funding

China Oral Health Foundation A2021-145Fund of Department of Oral and Maxillofacial Surgery 2022-05Shanghai Pudong New Area Health and Family Planning Commission joint projec PW2018D-10
6 · The paper itself

Abstract

backgroundThe study aimed to compare the dentoskeletal effects of Vanbeek Activator, Herbst, Twin-Block and Mandibular Advancement with clear aligners in children with skeletal Class II malocclusions.

methodsA sample with sixty-three patients (37 males, 26 females) was included and divided into untreated control group (C, n = 12), Vanbeek Activator group (V, n = 14), Herbst group (H, n = 11), Twin-Block group (TB, n = 12) and MA group (MA, n = 14). Cephalometric analysis and Johnston Pitchfork analysis were performed to quantify the skeletal and dentoalveolar components in molar relationship and overjet correction. Compare the differences of cephalometric data and Johnston-analysis data.

resultsThe treatment changes showed significant differences in SNB, FH-NP, NA-PA, Co-Go, Co-Pog, ANB, lower facial height ratio, U1-PP, U6-PP, L1-MP and U1-L1. All the appliances improved overjet relationships significantly (Vanbeek, Herbst, Twin-Block and MA were 2.77 mm, 5.53 mm, 4.73 mm and 3.66 mm respectively) with significant retraction of maxillary incisors. The lower incisor displacement of group V and MA was negative, while that of group H and TB was positive and there were significant differences. Molar relationships were also improved by 3.45 mm, 6.85 mm, 3.48 mm and 0.92 mm for Vanbeek, Herbst, Twin-Block and MA. Mandible displacement showed a trend of group H > TB > V > MA. The displacement of maxillary molars in group H was greater than that in group C, TB and MA, and that of mandibular ones was greater than that in group C, V and MA, significantly. Herbst, Twin-Block and MA have more significant dentoalveolar effect than Vanbeek, while Vanbeek has more skeletal effect than the others especially in restraining maxillary growth.

conclusionsFour appliances are all effective in mandibular advancement, modification of class II molar relationship and deep overjet, with unavoidable increase in lower facial ratio. Vanbeek Activator has the most skeletal effects. Vanbeek and MA have a good control of mandibular incisors while more compensatory lower incisors proclination in Herbst and Twin-Block. Herbst has greater maxillary molar distalization. MA allows aligning and leveling meanwhile leading the mandible forward.

Indexed as

Malocclusion, Angle Class IIMandibular AdvancementOrthodontic Appliances, FunctionalOrthodontic Appliances, RemovableCephalometryChildFemaleHumansIncisorMaleMandibleTreatment OutcomeCephalometricClass II malocclusionClear alignersFunctional appliancesJohnston’s Pitchfork Analysis

Identifiers

PMID36732724
PMCPMC9896678
OpenAlexW4318982712

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.