ArticleBMC oral health2023
Does mandibular advancement with clear aligners have the same skeletal and dentoalveolar effects as traditional functional appliances?
Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07608406 (Evaluation of the Efficacy of Functional Therapy Using Modified Twin Block Versus Clear Twin Block in Class II Skeletal Patients), which is not on this map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Efficacy of Functional Therapy Using Modified Twin Block Versus Clear Twin Block in Class II Skeletal Patients: A Randomized Controlled Clinical Trial
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Coefficient of efficiency and effectiveness of functional appliances in class II malocclusion treatment : A systematic review.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026Pooled it
- Comparative efficacy of clear aligner mandibular advancement versus traditional functional appliances for skeletal Class II malocclusion: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Precision wings treating skeletal class II in growing patients: a systematic review and meta-analysis.Progress in orthodontics · 2025Pooled it
- Comparison of Twin Block appliance and Herbst appliance in the treatment of Class II malocclusion among children: a meta-analysis.BMC oral health · 2024Pooled it
- Effects of clear aligners treatment in growing patients: a systematic review.Frontiers in oral health · 2024Pooled it
- The effect of mandibular advancement with clear aligners compared with activator therapy on maxillary and mandibular volumes: a randomized controlled trial using CBCT.BMC oral health · 2026Trial
- Comparative Evaluation of Modified Vacuum-Formed Aligners Versus Conventional Micro-Implant Anchorage in Molar Intrusion for Pre-Restorative Orthodontics.Orthodontics & craniofacial research · 2026Article
- Analysis of the efficacy of AngelAligner A6 mandibular advancer and Twin Block in the treatment of class II malocclusion in growing patients: a prospective clinical study.BMC oral health · 2026Article
- Efficacy of van Beek headgear activator in adolescents with UARS and hyperdivergent skeletal class II malocclusion: dentofacial morphology, airway, and growth.BMC oral health · 2026Article
- Comparative evaluation of the skeletal, dental, and soft-tissue effects of twin block, monoblock, and invisalign mandibular advancement appliances.BMC oral health · 2026Article
- Evaluation of the dental and skeletal effects of mandibular advancement by herbst appliance combined with miniscrews: a retrospective study.BMC oral health · 2026Article
- Efficacy of clear functional orthodontic appliances versus traditional functional appliances in the treatment of Class II malocclusion: A systematic review and meta-analysis.Korean journal of orthodontics · 2026Article
- Potential for vertical control using direct 3D‑printed mandibular advancement clear aligners.Clinical oral investigations · 2026Article
- Do treatment outcomes of clear aligners remain stable over time? A systematic review.Journal of orthodontic science · 2026Review
- A comparative 3D finite element analysis of mandibular advancement with clear aligners and twin block appliances.BMC oral health · 2025Article
- Retrospective Evaluation of InvisalignDentistry journal · 2025Article
- Treatment of class II malocclusion and ectopic maxillary canines: A case report.World journal of clinical cases · 2025Article
- Effectiveness of Clear Aligner Therapy in Orthodontic Management for Children with Mixed Dentition: A Scoping Review.International journal of clinical pediatric dentistry · 2025Review
- Evaluation of the efficacy of clear aligners in mandibular advancement and their effect on mandibular trabecular structures using fractal dimension analysis.BMC oral health · 2025Article
- Oral Implications of Herbst Device Modification: A Case Report.Children (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe study aimed to compare the dentoskeletal effects of Vanbeek Activator, Herbst, Twin-Block and Mandibular Advancement with clear aligners in children with skeletal Class II malocclusions.
methodsA sample with sixty-three patients (37 males, 26 females) was included and divided into untreated control group (C, n = 12), Vanbeek Activator group (V, n = 14), Herbst group (H, n = 11), Twin-Block group (TB, n = 12) and MA group (MA, n = 14). Cephalometric analysis and Johnston Pitchfork analysis were performed to quantify the skeletal and dentoalveolar components in molar relationship and overjet correction. Compare the differences of cephalometric data and Johnston-analysis data.
resultsThe treatment changes showed significant differences in SNB, FH-NP, NA-PA, Co-Go, Co-Pog, ANB, lower facial height ratio, U1-PP, U6-PP, L1-MP and U1-L1. All the appliances improved overjet relationships significantly (Vanbeek, Herbst, Twin-Block and MA were 2.77 mm, 5.53 mm, 4.73 mm and 3.66 mm respectively) with significant retraction of maxillary incisors. The lower incisor displacement of group V and MA was negative, while that of group H and TB was positive and there were significant differences. Molar relationships were also improved by 3.45 mm, 6.85 mm, 3.48 mm and 0.92 mm for Vanbeek, Herbst, Twin-Block and MA. Mandible displacement showed a trend of group H > TB > V > MA. The displacement of maxillary molars in group H was greater than that in group C, TB and MA, and that of mandibular ones was greater than that in group C, V and MA, significantly. Herbst, Twin-Block and MA have more significant dentoalveolar effect than Vanbeek, while Vanbeek has more skeletal effect than the others especially in restraining maxillary growth.
conclusionsFour appliances are all effective in mandibular advancement, modification of class II molar relationship and deep overjet, with unavoidable increase in lower facial ratio. Vanbeek Activator has the most skeletal effects. Vanbeek and MA have a good control of mandibular incisors while more compensatory lower incisors proclination in Herbst and Twin-Block. Herbst has greater maxillary molar distalization. MA allows aligning and leveling meanwhile leading the mandible forward.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.