ArticleBMC pediatrics2023
Clinical outcomes of pediatric osteomyelitis.
Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Short- versus long-course of antimicrobial treatment in pediatric population with acute osteoarticular infections: a systematic review and meta-analysis.European journal of pediatrics · 2026Pooled it
- The epidemiology and management of chronic osteomyelitis in pediatrics - A systematic review.PloS one · 2025Pooled it
- Osteomyelitis: Epidemiology, Classification, Pathophysiology, Clinical Features, Diagnosis, and Management.MedComm · 2026Review
- Osteomyelitis.Nature reviews. Disease primers · 2026Review
- Current trends in burden and management of pediatric osteomyelitis in the African continent: a systematic review of the last decade.Annals of medicine and surgery (2012) · 2026Article
- Imaging pediatric osteomyelitis: The role ofRadiology case reports · 2026Article
- Global research trends in pediatric bone and joint infections: A 50-year bibliometric analysis (1976-2025).SICOT-J · 2026Article
- A Study of 29 Pediatric Patients With Osteomyelitis Resulting From Neuropathy and Pressure Effects.Journal of tropical medicine · 2026Article
- Pathogen virulence and host response: A systematic review of severe illness in childhood musculoskeletal infection.Journal of clinical orthopaedics and trauma · 2026Review
- Systemic Infection of Pediatric Osteomyelitis: A Clinical Case in a Low-Income Country.Cureus · 2025Article
- Management of pathologic fracture of long bones as a complication of acute osteomyelitis: a challenging task for orthopedic surgeons.BMC musculoskeletal disorders · 2025Article
- Neonatal osteomyelitis: a case series and literature review.Translational pediatrics · 2025Article
- Pathological fractures in the paediatric orthopaedic patient population: a current concepts overview of assessment and management.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Review
- Article
- Effectiveness of the Pediatric Nursing Excellence Model on Nurses' Knowledge and Practice in Pediatric Orthopedic Surgery Care: A Randomized Controlled Trial.Children (Basel, Switzerland) · 2024Article
- Can jaw bone healed from chronic sclerosing osteomyelitis be considered healthy when planning dental implants? Case report with 20-year follow-up.Annals of medicine and surgery (2012) · 2024Article
- A transformer-based deep learning model for identifying the occurrence of acute hematogenous osteomyelitis and predicting blood culture results.Frontiers in microbiology · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundOsteomyelitis in children may produce severe sequelae. However, the frequency and distribution of such complications by type of osteomyelitis (chronic or acute) is not well described.
methodsWe searched the HealthFacts® database (containing medical information on 68 million individual patients in the United States) with 238 International Classification of Diseases (ICD) version 10 codes for acute osteomyelitis and chronic osteomyelitis appearing in 2015. Outcomes were recorded for each subject, including development of limb length discrepancies, pathologic fractures, mortality, and need for multiple surgeries or prolonged orthopedic care (one to two years following diagnosis). Gender, age and season of diagnosis were also assessed. Chi-square tests were used to compare differences between categorical variables, and t-tests between continuous variables.
resultsEight hundred sixty-nine subjects were included (57.4% male). Children with chronic osteomyelitis were older than those with acute osteomyelitis (median 9.5 years vs 12.0, respectively, p = .0004). Diagnoses were more common in winter (p = .0003). Four subjects died while hospitalized during the study period (two with acute osteomyelitis, two with chronic osteomyelitis). Limb length discrepancies were rare and similarly distributed between infection types (≤ 1.3% of subjects, p = .83). Subjects with chronic osteomyeltis were more likely to require long-term orthopedic follow-up (14.0% vs. 4.8% for acute osteomyelitis, p < .0001), suffer from pathologic fractures (1.5% vs < 1.0%, p = .003) and to require multiple surgeries (46.0% vs. 29.3%, p = .04).
conclusionsThough infrequent, serious outcomes from osteomyelitis are more common with chronic osteomyelitis than acute osteomyelitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.