Evidence map›Paper›PMID 36732689›Full record

ArticleBMC cardiovascular disorders2023

Association of the bovine aortic arch and bicuspid aortic valve with thoracic aortic disease.

Jing Sun, Shuai Zhang, Hongxia Qi, Cheng Sun, Zhihui Hou, Xiaoqi Wang, Xiangyang Qian

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jing Sun *Department of Cardiovascular Surgery, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 167, North Lishi Street, Xicheng District, Beijing, China.
Shuai Zhang *Department of Cardiovascular Surgery, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 167, North Lishi Street, Xicheng District, Beijing, China.
Hongxia QiDepartment of Medical Imaging, Ultrasound Division, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Cheng SunDepartment of Cardiovascular Surgery, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 167, North Lishi Street, Xicheng District, Beijing, China.
Zhihui HouDepartment of Radiologic Imaging, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Xiaoqi WangDepartment of Cardiovascular Surgery, Yunnan Fuwai Cardiovascular Hospital, Kunming, China.
Xiangyang QianDepartment of Cardiovascular Surgery, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 167, North Lishi Street, Xicheng District, Beijing, China. m13701097213@163.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNFuwai Yunnan Cardiovascular Hospital · CN

Funding

Fundamental Research Funds for the Central Universities 3332021021Yunnan Provincial Cardiovascular Disease Clinical Medical Center Project FZX2019-06-01
6 · The paper itself

Abstract

backgroundBoth bicuspid aortic valve (BAV) and bovine aortic arch (BA) are considered as markers of thoracic aortic disease (TAD). But the association between them is not yet clear. This study aimed to explore the potential association of BAV and BA with TAD.

methodsThe study involved 449 participants who underwent their first aortic valve replacement in Fuwai Hospital from June 2017 to March 2018. All patients underwent multidetector computed tomography and echocardiography before surgery. The clinical characteristics were recorded to analyze the association between BAV, BA, and TAD. The univariate and multivariate logistic regression analyses were applied to identify the risk factors for TAD.

resultsBA accounted for 79.8% of the arch variants and was the most common aortic arch branching variant. BAV was present in 52.6% of the patients with BA and 38.1% of the patients with normal arch (NA). Among the 185 patients in the BAV subgroup, 50 had BA and 135 had NA. No significant differences were found in BAV anatomical phenotype, aortopathy phenotype, and valve function between BA and NA. The multivariate analysis showed that the presence of BAV and male sex were the risk predictors of TAD. BA was not a risk factor for TAD in either univariate or multivariate analysis.

conclusionsThe proportion of BAV in patients with BA was significantly higher than that of NA, but the BAV phenotype and aortopathy were not related to BA. BAV was a risk factor for TAD, whereas BA was not associated with TAD.

Indexed as

Aortic DiseasesBicuspid Aortic Valve DiseaseHeart Valve DiseasesAorta, ThoracicAortic ValveHumansMaleBicuspid aortic valveBicuspid aortopathyBovine aortic archThoracic aortic disease

Identifiers

PMID36732689
PMCPMC9893652
OpenAlexW4318984207

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.