Evidence map›Paper›PMID 36732682›Full record

ArticleBMC geriatrics2023

Genetic and environmental influences on fruit and vegetable consumption and depression in older adults.

Annabel P Matison, Anbupalam Thalamuthu, Victoria M Flood, Julian N Trollor, Vibeke S Catts, Margaret J Wright, David Ames, Henry Brodaty, Perminder S Sachdev, Simone Reppermund and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Annabel P MatisonCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, UNSW Sydney, Level 1, AGSM (G27) Gate 11, Botany Street, Sydney, NSW, 2052, Australia. a.matison@unsw.edu.au.
Anbupalam ThalamuthuCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, UNSW Sydney, Level 1, AGSM (G27) Gate 11, Botany Street, Sydney, NSW, 2052, Australia.
Victoria M FloodFaculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Julian N TrollorCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, UNSW Sydney, Level 1, AGSM (G27) Gate 11, Botany Street, Sydney, NSW, 2052, Australia.
Vibeke S CattsCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, UNSW Sydney, Level 1, AGSM (G27) Gate 11, Botany Street, Sydney, NSW, 2052, Australia.
Margaret J WrightQueensland Brain Institute, University of Queensland, Brisbane, QLD, Australia.
David AmesAcademic Unit for Psychiatry of Old Age, University of Melbourne, St George's Hospital, Melbourne, VIC, Australia.
Henry BrodatyCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, UNSW Sydney, Level 1, AGSM (G27) Gate 11, Botany Street, Sydney, NSW, 2052, Australia.
Perminder S SachdevCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, UNSW Sydney, Level 1, AGSM (G27) Gate 11, Botany Street, Sydney, NSW, 2052, Australia.
Simone Reppermund *Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, UNSW Sydney, Level 1, AGSM (G27) Gate 11, Botany Street, Sydney, NSW, 2052, Australia.
Karen A Mather *Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, UNSW Sydney, Level 1, AGSM (G27) Gate 11, Botany Street, Sydney, NSW, 2052, Australia.
UNSW Sydney · AUNational Imaging Facility · AUPrince of Wales Hospital · AUUniversity of Melbourne · AUUniversity of Sydney · AU

Funding

Australian Research Council 401162National Health & Medical Research Council 1025243National Health & Medical Research Council 1045325National Health & Medical Research Council 1085606National Health & Medical Research Council 1093083National Health & Medical Research Council 568969National Health and Medical Research Council 1024224
6 · The paper itself

Abstract

backgroundPrior work suggests that higher fruit and vegetable consumption may protect against depression in older adults. Better understanding of the influence of genetic and environmental factors on fruit and vegetable intakes may lead to the design of more effective dietary strategies to increase intakes. In turn this may reduce the occurrence of depression in older adults.

objectivesThe primary aim of this study is to estimate the genetic and environmental influences on the consumption of fruit and vegetables in older adults. The secondary aim is an exploratory analysis into possible shared genetic influences on fruit and vegetable intakes and depression.

methodsAnalysis of observational data from 374 twins (67.1% female; 208 monozygotic (MZ); 166 dizygotic (DZ)) aged ≥ 65 years drawn from the Older Australian Twins Study. Dietary data were obtained using a validated food frequency questionnaire and depressive symptoms were measured using the 15-item short form Geriatric Depression Scale. The contribution of genetic and environmental influences on fruit and vegetable intake were estimated by comparing MZ and DZ twin intakes using structural equation modelling. A tri-variate twin model was used to estimate the genetic and environmental correlation between total fruit and vegetable intakes and depression.

resultsIn this study, vegetable intake was moderately influenced by genetics (0.39 95%CI 0.22, 0.54). Heritability was highest for brassica vegetables (0.40 95%CI 0.24, 0.54). Overall fruit intake was not significantly heritable. No significant genetic correlations were detected between fruit and vegetable intake and depressive symptoms.

conclusionsVegetable consumption, particularly bitter tasting brassica vegetables, was significantly influenced by genetics, although environmental influences were also apparent. Consumption of fruit was only influenced by the environment, with no genetic influence detected, suggesting strategies targeting the food environment may be particularly effective for encouraging fruit consumption.

Indexed as

FruitVegetablesAgedAustraliaDepressionDietFeeding BehaviorFemaleHumansMaleDepressionFruitGeneticsHeritabilityTwin studyVegetables

Identifiers

PMID36732682
PMCPMC9896753
OpenAlexW4318946203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.