Evidence map›Paper›PMID 36732559›Full record

ArticleScientific reports2023

Association of combustible cigarettes and heated tobacco products use with SARS-CoV-2 infection and severe COVID-19 in Japan: a JASTIS 2022 cross-sectional study.

Misako Nishimura, Kazuhisa Asai, Takahiro Tabuchi, Erika Toyokura, Takahiro Kawai, Atsushi Miyamoto, Tetsuya Watanabe, Tomoya Kawaguchi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. JSH2024 smoke-free declaration "Stop All Tobacco Products".Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Misako NishimuraDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, 1-4-3, Asahimachi, Abeno-Ku, Osaka, 545-8585, Japan.
Kazuhisa AsaiDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3, Asahimachi, Abeno-Ku, Osaka, 545-8585, Japan. kazuasai@omu.ac.jp.
Takahiro TabuchiCancer Control Center, Osaka International Cancer Institute, 1-69, Ohtemae 3-Chome, Chuo-Ku, Osaka, 541-8567, Japan.
Erika ToyokuraDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, 1-4-3, Asahimachi, Abeno-Ku, Osaka, 545-8585, Japan.
Takahiro KawaiDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, 1-4-3, Asahimachi, Abeno-Ku, Osaka, 545-8585, Japan.
Atsushi MiyamotoDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3, Asahimachi, Abeno-Ku, Osaka, 545-8585, Japan.
Tetsuya WatanabeDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3, Asahimachi, Abeno-Ku, Osaka, 545-8585, Japan.
Tomoya KawaguchiDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3, Asahimachi, Abeno-Ku, Osaka, 545-8585, Japan.
Osaka City University · JPOsaka Metropolitan UniversityOsaka International Cancer Institute · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insufficient evidence has been accumulated regarding associations of heated tobacco products (HTPs) use with coronavirus infection and severity of coronavirus disease 2019 (COVID-19), an ongoing pandemic. We conducted a cross-sectional study using data from an internet questionnaire administered in February 2022 to 30,130 individuals from the general Japanese population (age range, 16-81 years). Single users of HTPs and dual users of combustible cigarettes and HTPs comprised 5.2% and 7.3% of respondents, and 6.7% and 38.0% of those infected (n = 1117). Approximately 70% of infected dual users experienced severe disease. Single users of HTPs and dual users were more likely to be infected with coronavirus than never-users (adjusted odds ratio [aOR] = 1.65/4.66; 95% confidence interval [CI] 1.26-2.15/3.89-5.58). Regarding severity, former and current tobacco users (former/combustible cigarettes/HTPs: aOR = 1.88/3.17/1.90; 95%CI 1.11-3.19/1.77-5.67/1.01-3.59) were more likely to be administered oxygen than never-users, and dual users required oxygen administration the most (aOR = 4.15, 95%CI 2.70-6.36). Use of HTPs may increase risks of coronavirus infection and severe COVID-19. Our results provide an opportunity to consider the safety of tobacco products use, including HTPs, during the COVID-19 pandemic.

Indexed as

COVID-19Electronic Nicotine Delivery SystemsTobacco ProductsAdolescentAdultAgedAged, 80 and overCross-Sectional StudiesHumansJapanMiddle AgedPandemicsSARS-CoV-2Surveys and QuestionnairesTobacco UseYoung Adult

Identifiers

PMID36732559
PMCPMC9894839
OpenAlexW4319002053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.