Evidence map›Paper›PMID 36732269›Full record

ArticleThe Journal of the Acoustical Society of America2023

Monitoring cavitation dynamics evolution in tissue mimicking hydrogels for repeated exposures via acoustic cavitation emissions.

Scott C Haskell, Ning Lu, Greyson E Stocker, Zhen Xu, Jonathan R Sukovich

Open access · greenAbstract read
In one paragraph

Article in The Journal of the Acoustical Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Scott C HaskellDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48105, USA.ORCID 0000-0003-1752-7573
Ning LuDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48105, USA.
Greyson E StockerDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48105, USA.
Zhen XuDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48105, USA.
Jonathan R SukovichDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48105, USA.
University of Michigan · US

Funding

Acoustic Cavitation Emission (ACE) Feedback Methods for Monitoring Histotripsy-Induced Tissue Fractionation In SituR01EB032772 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SUKOVICH, JONATHAN ROBERT · 2022 to 2025
$2.0M
NIBIB NIH HHS R01 EB032772
6 · The paper itself

Abstract

A 700 kHz histotripsy array is used to generate repeated cavitation events in agarose, gelatin, and polyacrylamide hydrogels. High-speed optical imaging, a broadband hydrophone, and the narrow-band receive elements of the histotripsy array are used to capture bubble dynamics and acoustic cavitation emissions. Bubble radii, lifespan, shockwave amplitudes are noted to be measured in close agreement between the different observation methods. These features also decrease with increasing hydrogel stiffness for all of the tested materials. However, the evolutions of these properties during the repeated irradiations vary significantly across the different material subjects. Bubble maximum radius initially increases, then plateaus, and finally decreases in agarose, but remains constant across exposures in gelatin and polyacrylamide. The bubble lifespan increases monotonically in agarose and gelatin but decreases in polyacrylamide. Collapse shockwave amplitudes were measured to have different-shaped evolutions between all three of the tested materials. Bubble maximum radii, lifespans, and collapse shockwave amplitudes were observed to express evolutions that are dependent on the structure and stiffness of the nucleation medium.

Indexed as

High-Intensity Focused Ultrasound AblationAcousticsGelatinHumansHydrogelsSepharoseGelatinHydrogelsSepharose

Identifiers

PMID36732269
PMCPMC10162839
OpenAlexW4316037437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.