ArticleThe Journal of the Acoustical Society of America2023
The middle ear muscle reflex: Current and future role in assessing noise-induced cochlear damage.
Article in The Journal of the Acoustical Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Broadband Noise Acoustic Stapedial Reflex Thresholds as a Marker of Cochlear and Neural Integrity in Individuals with Normal Audiograms.Audiology research · 2026Article
- Migraine impairs the auditory protective mechanism: a potential biomarker.The journal of headache and pain · 2026Article
- Rapid Characterization of Middle-Ear Muscle Reflexes Using Swept Elicitors.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
- Advanced methodology for damping characterization of the human tympanic membrane using high-speed digital holography and STFT analysis.Scientific reports · 2026Article
- Advanced Methodology for Damping Characterization of the Human Tympanic Membrane Using High-Speed Digital Holographic and STFT Analysis.Research square · 2026Article
- Attention to speech modulates distortion product otoacoustic emissions evoked by speech-derived stimuli in humans.Frontiers in neuroscience · 2026Article
- A Critique of the Stenger Test.Audiology research · 2025Article
- Deep phenotyping to understand hearing and hearing disorders: Protocol for a feasibility study.PloS one · 2025Article
- Accuracy and Repeatability of ChatGPT Based on a Set of Multiple-Choice Questions on Objective Tests of Hearing.Cureus · 2024Article
- Noise-induced hearing disorders: Clinical and investigational tools.The Journal of the Acoustical Society of America · 2023Article
- Perceptual Consequences of Cochlear Deafferentation in Humans.Trends in hearingReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The middle ear muscle reflex (MEMR) in humans is a bilateral contraction of the middle ear stapedial muscle in response to moderate-to-high intensity acoustic stimuli. Clinically, MEMR thresholds have been used for differential diagnosis of otopathologies for decades. More recently, changes in MEMR amplitude or threshold have been proposed as an assessment for noise-induced synaptopathy, a subclinical form of cochlear damage characterized by suprathreshold hearing problems that occur as a function of inner hair cell (IHC) synaptic loss, including hearing-in-noise deficits, tinnitus, and hyperacusis. In animal models, changes in wideband MEMR immittance have been correlated with noise-induced synaptopathy; however, studies in humans have shown more varied results. The discrepancies observed across studies could reflect the heterogeneity of synaptopathy in humans more than the effects of parametric differences or relative sensitivity of the measurement. Whereas the etiology and degree of synaptopathy can be carefully controlled in animal models, synaptopathy in humans likely stems from multiple etiologies and thus can vary greatly across the population. Here, we explore the evolving research evidence of the MEMR response in relation to subclinical noise-induced cochlear damage and the MEMR as an early correlate of suprathreshold deficits.
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