Evidence map›Paper›PMID 36732229›Full record

ArticleThe Journal of the Acoustical Society of America2023

Effect of nodule size and stiffness on phonation threshold and collision pressures in a synthetic hemilaryngeal vocal fold model.

Mohsen Motie-Shirazi, Matías Zañartu, Sean D Peterson, Daryush D Mehta, Robert E Hillman, Byron D Erath

Abstract read
In one paragraph

Article in The Journal of the Acoustical Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Biomechanical Mechanisms of Vocal Fold Nodule and Polyp Formation: A Review.Journal of voice : official journal of the Voice Foundation · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Synthetic, self-oscillating vocal fold models for voice production researcha).The Journal of the Acoustical Society of America · 2024
    Review
  6. Mechanotransduction in the Vocal Fold Microenvironment: A Narrative Review.Journal of speech, language, and hearing research : JSLHR · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohsen Motie-ShiraziDepartment of Mechanical and Aerospace Engineering, Clarkson University, Potsdam, New York 13699, USA.ORCID 0000-0002-0168-0330
Matías ZañartuDepartment of Electronic Engineering, Universidad Técnica Federico Santa María, Valparaíso, Chile.ORCID 0000-0001-5581-4392
Sean D PetersonDepartment of Mechanical and Mechatronics Engineering, University of Waterloo, Waterloo, Ontario, Canada.ORCID 0000-0001-8746-2491
Daryush D MehtaCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.ORCID 0000-0002-6535-573X
Robert E HillmanCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.ORCID 0000-0002-7374-994X
Byron D ErathDepartment of Mechanical and Aerospace Engineering, Clarkson University, Potsdam, New York 13699, USA.ORCID 0000-0003-0057-6731

Funding

Use of ambulatory biofeedback to improve behavioral treatment of vocal hyperfunctionP50DC015446 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI Jarrad Van Stan · 2017 to 2026
$25.5M
NIDCD NIH HHS P50 DC015446
6 · The paper itself

Abstract

Synthetic vocal fold (VF) replicas were used to explore the role of nodule size and stiffness on kinematic, aerodynamic, and acoustic measures of voiced speech production. Emphasis was placed on determining how changes in collision pressure may contribute to the development of phonotrauma. This was performed by adding spherical beads with different sizes and moduli of elasticity at the middle of the medial surface of synthetic silicone VF models, representing nodules of varying size and stiffness. The VF models were incorporated into a hemilaryngeal flow facility. For each case, self-sustained oscillations were investigated at the phonation threshold pressure. It was found that increasing the nodule diameter increased the open quotient, phonation threshold pressure, and phonation threshold flow rate. However, these values did not change considerably as a function of the modulus of elasticity of the nodule. Nevertheless, the ratio of collision pressure to subglottal pressure increased significantly for both increasing nodule size and stiffness. This suggests that over time, both growth in size and fibrosis of nodules will lead to an increasing cycle of compensatory vocal hyperfunction that accelerates phonotrauma.

Indexed as

VibrationVocal CordsElasticityPhonationPressure

Identifiers

PMID36732229
PMCPMC9884154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.