Evidence map›Paper›PMID 36731940›Full record

ArticleBMJ case reports2023

Amelioration of trichotillomania with onabotulinumtoxinA for chronic migraine.

Emily Rubenstein Engel, Jeremy-Ann Ham

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Emily Rubenstein EngelDepartment of Neurology, Scripps Clinic, La Jolla, California, USA engel.emily@scrippshealth.org.
Jeremy-Ann HamDepartment of Medicine, Scripps Green Hospital, La Jolla, California, USA.
Scripps Clinic · USScripps Green Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a woman in her 30s who struggled with a life-long history of trichotillomania (TTM; hair-pulling disorder), which was unsuccessfully treated with behavioural therapy and selective serotonin reuptake inhibitors. In addition to TTM, our patient had a history of chronic migraine which brought her to our clinic, and treatment with onabotulinumtoxinA (OBTA) was initiated per the Phase III REsearch Evaluating Migraine Prophylaxis Therapy protocol. After experiencing improvement with migraine symptoms, she began off-label treatment with OBTA for her TTM with 45 units being injected, 5 units per site, in diffuse regions of her scalp, primarily on the affected areas of TTM-induced alopecia. The patient reported marked improvement in her TTM signs and symptoms, which resulted in hair regrowth as early as the first follow-up visit 12 weeks post-treatment initiation. Treatment effects were maintained, and additional hair regrowth was observed at the 1-year post-treatment visit, which equated to four cycles of treatment.

Indexed as

Botulinum Toxins, Type AMigraine DisordersTrichotillomaniaAlopeciaFemaleHumansSelective Serotonin Reuptake InhibitorsBotulinum Toxins, Type ASelective Serotonin Reuptake InhibitorsAnxiety disorders (including OCD and PTSD)Botulinum toxinHeadache (including migraines)Neurology (drugs and medicines)Psychiatry (drugs and medicines)

Identifiers

PMID36731940
PMCPMC9896224
OpenAlexW4318987680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.