Evidence map›Paper›PMID 36731891›Full record

ArticleJournal for immunotherapy of cancer2023

BRCA1 deficiency in mature CD8

Bogang Wu, Leilei Qi, Huai-Chin Chiang, Haihui Pan, Xiaowen Zhang, Alexandra Greenbaum, Elizabeth Stark, Li-Ju Wang, Yidong Chen, Bassem R Haddad and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. GermlineImmuno-oncology technology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Terminally exhausted CD8Frontiers in immunology · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. ConstitutionalInternational journal of molecular sciences · 2024
    Article
  14. Review
  15. MicroRNA-155-5p, Reduced by Curcumin-Re-Expressed HypermethylatedInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Bogang Wu *Department of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA.ORCID 0000-0003-1654-198X
Leilei Qi *Department of Anatomy & Cell Biology, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA.
Huai-Chin ChiangDepartment of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA.
Haihui PanDepartment of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA.
Xiaowen ZhangDepartment of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA.
Alexandra GreenbaumRuth Paul Cancer Genetics and Prevention Program, Medical Faculty Associates, The George Washington University, Washington, District of Columbia, USA.
Elizabeth StarkRuth Paul Cancer Genetics and Prevention Program, Medical Faculty Associates, The George Washington University, Washington, District of Columbia, USA.
Li-Ju WangDepartment of Biostatistics, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Yidong ChenDepartment of Biostatistics, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Bassem R HaddadLombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA.
Dionyssia ClagettLombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA.
Claudine IsaacsLombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA.
Richard ElledgeSan Antonio State Hospital, San Antonio, Texas, USA.
Anelia HorvathDepartment of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA.
Yanfen HuDepartment of Anatomy & Cell Biology, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA.
Rong LiDepartment of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA rli69@gwu.edu.
George Washington University · USGeorgetown University · USThe University of Texas Health Science Center at San Antonio · USState Hospital · GB

Funding

Boosting Antitumor Immunity by Blocking Both Tumor and Adipose DDR1R01CA246707 · NCI · GEORGE WASHINGTON UNIVERSITY · PI LI, RONG · 2020 to 2024
$2.3M
Crosstalk between BRCA1 and Transcription in Breast CancerR01CA220578 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LI, RONG · 2017 to 2022
$2.1M
Role of BRCA1 phosphorylation in DNA DSB repair and genome stability maintenanceR01CA212674 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HU, YANFEN, LI, RONG · 2017 to 2022
$1.9M
NCI NIH HHS R01 CA212674NCI NIH HHS R01 CA220578NCI NIH HHS R01 CA246707
6 · The paper itself

Abstract

Women with

Indexed as

Antineoplastic AgentsNeoplasmsAnimalsCarcinogenesisCD8-Positive T-LymphocytesFemaleImmunityMiceMice, KnockoutAntineoplastic AgentsAdaptive ImmunityBreast NeoplasmsCD8-Positive T-Lymphocytes

Identifiers

PMID36731891
PMCPMC9896206
OpenAlexW4318987677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.