ArticleUltraschall in der Medizin (Stuttgart, Germany : 1980)2023
Contrast-Enhanced Ultrasound and Strain Elastography for Differentiating Benign and Malignant Parotid Tumors.
Article in Ultraschall in der Medizin (Stuttgart, Germany : 1980), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
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Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- CEUS in the evaluation of focal salivary gland lesions: a systematic review.Journal of ultrasound · 2026Pooled it
- Comparative analysis of elastosonography and 18 F-FDG PET/CT in differentiating benign and malignant salivary gland tumors: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Ultrasonic viscoelastic imaging: a tool for parotid gland tumor differentiation.European radiology · 2026Article
- A case report of misdiagnosed adenoid cystic carcinoma of the parotid gland on ultrasound: imaging-pathological correlation and diagnostic implications.Gland surgery · 2025Article
- Ultrasound-Based Deep Learning Radiomics Models for Predicting Primary and Secondary Salivary Gland Malignancies: A Multicenter Retrospective Study.Bioengineering (Basel, Switzerland) · 2025Article
- Comparison of Color Doppler Ultrasound Characteristics between Parotid Mucoepidermoid Carcinoma and Basal Cell Adenoma.Journal of medical ultrasoundArticle
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5 authors.
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Abstract
objectivesPreoperative differentiation between benign parotid tumors (BPT) and malignant parotid tumors (MPT) is crucial for treatment decisions. The purpose of this study was to investigate the benefits of combining contrast-enhanced ultrasound (CEUS) and strain elastography (SE) for preoperative differentiation between BPT and MPT.
methodsA total of 115 patients with BPT (n=72) or MPT (n=43) who underwent ultrasound (US), SE, and CEUS were enrolled. US and CEUS features and the elasticity score were evaluated. Receiver operating characteristic curve (ROC) analysis was used to assess the diagnostic performance of SE, CEUS, and SE + CEUS with respect to identifying MPT from BPT.
resultsSolitary presentation, larger diameter, irregular shape, ill-defined margin, heterogeneous echogenicity, and calcification on US and higher elasticity score on SE had a significant association with malignancy. MPT also presented an unclear margin, larger size after enhancement, and "fast-in and fast-out" pattern on CEUS. The combination of SE and CEUS was effective for differentiating MPT from BPT (AUC: 0.88, 0.80-0.95), with a sensitivity of 86.0%, specificity of 88.9%, and accuracy of 87.8%, which were significantly higher than the values for SE (AUC: 0.75, 0.66-0.85) and CEUS (AUC: 0.82, 0.73-0.91) alone.
conclusionThe combination of CEUS and SE is valuable for distinguishing MPT from BPT.
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