Evidence map›Paper›PMID 36731126›Full record

ArticleACS synthetic biology2023

Tail-Engineered Phage P2 Enables Delivery of Antimicrobials into Multiple Gut Pathogens.

Jidapha Fa-Arun, Yang Wei Huan, Elise Darmon, Baojun Wang

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jidapha Fa-ArunSchool of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FF, United Kingdom.
Yang Wei HuanSchool of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FF, United Kingdom.ORCID 0000-0001-6723-3093
Elise DarmonSchool of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FF, United Kingdom.
Baojun WangCollege of Chemical and Biological Engineering & ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-4858-8937
University of Edinburgh · GBZhejiang Lab · CN

Funding

Medical Research Council MR/S018875/1
6 · The paper itself

Abstract

Bacteriophages can be reprogrammed to deliver antimicrobials for therapeutic and biocontrol purposes and are a promising alternative treatment to antimicrobial-resistant bacteria. Here, we developed a bacteriophage P4 cosmid system for the delivery of a Cas9 antimicrobial into clinically relevant human gut pathogens

Indexed as

Bacteriophage P2BacteriophagesEscherichia coli O157Humansbacteriophage P2/P4Cas9 antimicrobialEscherichia coli O157:H7phage-based delivery vectorShigella flexneritail fiber engineering

Identifiers

PMID36731126
PMCPMC9942202
OpenAlexW4318947353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.