ArticlePloS one2023
Exploring facial expressions and action unit domains for Parkinson detection.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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16 citing papers in PubMed, 33 citations in OpenAlex.
- Privacy-Aware Synthetic Tabular Data Generation for Healthcare: Application to Sepsis Detection.Bioengineering (Basel, Switzerland) · 2026Article
- Facial Expression Annotation and Analytics for Dysarthria Severity Classification.Sensors (Basel, Switzerland) · 2026Article
- Speech Impairment in Early Parkinson's Disease Is Associated with Nigrostriatal Dopaminergic Dysfunction.Journal of clinical medicine · 2026Article
- Machine Learning-Based Detection of Parkinson's Disease From Arabic Speech: A Cross-Linguistic Validation Study.Journal of central nervous system disease · 2026Article
- Facial Expression Metrics as Digital Biomarkers of Neurologic Disease.Neurology open access · 2025Article
- Explaining facial action units' correlation with hypomimia and clinical scores in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Correction: Exploring facial expressions and action unit domains for Parkinson detection.PloS one · 2025Article
- Motor symptoms of Parkinson's disease: critical markers for early AI-assisted diagnosis.Frontiers in aging neuroscience · 2025Review
- Automated identification of early to mid-stage Parkinson's disease using deep convolutional neural networks on static facial images.Frontiers in medical technology · 2025Article
- Synchronous Analysis of Speech Production and Lips Movement to Detect Parkinson's Disease Using Deep Learning Methods.Diagnostics (Basel, Switzerland) · 2024Article
- Multimodal Technologies for Remote Assessment of Neurological and Mental Health.Journal of speech, language, and hearing research : JSLHR · 2024Review
- The Story behind the Mask: A Narrative Review on Hypomimia in Parkinson's Disease.Brain sciences · 2024Review
- Utilizing deep learning models in an intelligent spiral drawing classification system for Parkinson's disease classification.Frontiers in medicine · 2024Article
- Deep Learning and Artificial Intelligence Applied to Model Speech and Language in Parkinson's Disease.Diagnostics (Basel, Switzerland) · 2023Article
- Quantitative Evaluation of Hypomimia in Parkinson's Disease: A Face Tracking Approach.Sensors (Basel, Switzerland) · 2022Article
- Speech dysfunction, cognition, and Parkinson's disease.Progress in brain research · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivePatients suffering from Parkinson's disease (PD) present a reduction in facial movements called hypomimia. In this work, we propose to use machine learning facial expression analysis from face images based on action unit domains to improve PD detection. We propose different domain adaptation techniques to exploit the latest advances in automatic face analysis and face action unit detection.
methodsThree different approaches are explored to model facial expressions of PD patients: (i) face analysis using single frame images and also using sequences of images, (ii) transfer learning from face analysis to action units recognition, and (iii) triplet-loss functions to improve the automatic classification between patients and healthy subjects.
resultsReal face images from PD patients show that it is possible to properly model elicited facial expressions using image sequences (neutral, onset-transition, apex, offset-transition, and neutral) with accuracy improvements of up to 5.5% (from 72.9% to 78.4%) with respect to single-image PD detection. We also show that our proposed action unit domain adaptation provides improvements of up to 8.9% (from 78.4% to 87.3%) with respect to face analysis. Finally, we also show that triplet-loss functions provide improvements of up to 3.6% (from 78.8% to 82.4%) with respect to action unit domain adaptation applied upon models created from scratch. The code of the experiments is available at https://github.com/luisf-gomez/Explorer-FE-AU-in-PD.
conclusionsDomain adaptation via transfer learning methods seem to be a promising strategy to model hypomimia in PD patients. Considering the good results and also the fact that only up to five images per participant are considered in each sequence, we believe that this work is a step forward in the development of inexpensive computational systems suitable to model and quantify problems of PD patients in their facial expressions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.