Evidence map›Paper›PMID 36729942›Full record

ArticlePlastic and reconstructive surgery2023

Paravertebral Blocks in Tissue Expander Breast Reconstruction: Propensity-Matched Analysis of Opioid Consumption and Patient Outcomes.

Meghana G Shamsunder, Jacqueline J Chu, Erin Taylor, Thais O Polanco, Robert J Allen, Tracy-Ann Moo, Joseph J Disa, Babak J Mehrara, Hanae K Tokita, Jonas A Nelson

Open access · greenAbstract read
In one paragraph

Article in Plastic and reconstructive surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Meghana G ShamsunderFrom the Plastic and Reconstructive Surgery Service.
Jacqueline J ChuFrom the Plastic and Reconstructive Surgery Service.
Erin TaylorFrom the Plastic and Reconstructive Surgery Service.
Thais O PolancoFrom the Plastic and Reconstructive Surgery Service.
Robert J AllenFrom the Plastic and Reconstructive Surgery Service.
Tracy-Ann MooBreast Surgery Service.
Joseph J DisaFrom the Plastic and Reconstructive Surgery Service.
Babak J MehraraFrom the Plastic and Reconstructive Surgery Service.
Hanae K TokitaAnesthesiology Service, Memorial Sloan Kettering Cancer Center.
Jonas A NelsonFrom the Plastic and Reconstructive Surgery Service.
Memorial Sloan Kettering Cancer Center · USHealth First · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundThe paravertebral block (PVB) is an adjunctive perioperative pain control method for patients undergoing breast reconstruction that may improve perioperative pain control and reduce narcotic use. This study determined the efficacy of preoperative PVBs for perioperative pain management in patients undergoing tissue expander breast reconstruction.

methodsA retrospective review was performed of patients who underwent tissue expander breast reconstruction from December of 2017 to September of 2019. Two patients with PVBs were matched using propensity scoring to one no-block patient. Perioperative analgesic use, pain severity scores on days 2 to 10 after discharge, and BREAST-Q Physical Well-Being scores before surgery and at 2 weeks, 6 weeks, and 3 months after surgery were compared between the two groups.

resultsThe propensity-matched cohort consisted of 471 patients (314 PVB and 157 no block). The PVB group used significantly fewer morphine milligram equivalents than the no-block group (53.7 versus 69.8; P < 0.001). Average daily postoperative pain severity scores were comparable, with a maximum difference of 0.3 points on a 0-point to 4-point scale. BREAST-Q Physical Well-Being scores were significantly higher for the PVB group than the no-block group at 6 weeks after surgery (60.6 versus 51.0; P = 0.015) but did not differ significantly at 2 weeks or 3 months after surgery.

conclusionsPVBs may help reduce perioperative opioid requirements but did not reduce pain scores after discharge when used as part of an expander-based reconstruction perioperative pain management protocol. Continued research should examine additional or alternative regional block procedures as well as financial cost and potential long-term impact of PVBs. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.

Indexed as

MammaplastyNerve BlockAnalgesics, OpioidHumansPostoperative PainTissue Expansion DevicesAnalgesics, Opioid

Identifiers

PMID36729942
PMCPMC10065883
OpenAlexW4318914586

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.