Evidence map›Paper›PMID 36729771›Full record

ArticleNursing research

Latent Class Analysis of Depressive Symptom Phenotypes Among Black/African American Mothers.

Nicole Beaulieu Perez, Gail D'Eramo Melkus, Fay Wright, Gary Yu, Allison A Vorderstrasse, Yan V Sun, Cindy A Crusto, Jacquelyn Y Taylor

Open access · greenAbstract read
In one paragraph

Article in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. EPA guidance on cultural competence training: a critical update and meta-review.European psychiatry : the journal of the Association of European Psychiatrists · 2026
    Pooled it
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  7. Stress-induced developmental plasticity and spontaneous preterm birth: A justice-oriented eco-evo-devo review.European journal of obstetrics & gynecology and reproductive biology: X · 2025
    Review
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  11. Heterogeneous depressive symptom trajectories among women with type 2 diabetes: findings from the Women's Interagency HIV Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Apple (Israel) · ILNew York Academy of Medicine · US

Funding

NRSA Training CoreTL1TR001447 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MICOLI, KEITH J. · 2015 to 2025
$5.9M
Intergenerational Impact of Genetic and Psychological Factors on Blood PressureR01NR013520 · NINR · YALE UNIVERSITY · PI TAYLOR, JACQUELYN Y · 2014 to 2019
$3.9M
NCATS NIH HHS TL1 TR001447NINR NIH HHS R01 NR013520
6 · The paper itself

Abstract

backgroundDepression is a growing global problem with significant individual and societal costs. Despite their consequences, depressive symptoms are poorly recognized and undertreated because wide variation in symptom presentation limits clinical identification-particularly among African American (AA) women-an understudied population at an increased risk of health inequity.

objectivesThe aims of this study were to explore depressive symptom phenotypes among AA women and examine associations with epigenetic, cardiometabolic, and psychosocial factors.

methodsThis cross-sectional, retrospective analysis included self-reported Black/AA mothers from the Intergenerational Impact of Genetic and Psychological Factors on Blood Pressure study (data collected in 2015-2020). Clinical phenotypes were identified using latent class analysis. Bivariate logistic regression examined epigenetic age, cardiometabolic traits (i.e., body mass index ≥ 30 kg/m 2 , hypertension, or diabetes), and psychosocial variables as predictors of class membership.

resultsAll participants were Black/AA and predominantly non-Hispanic. Over half of the sample had one or more cardiometabolic traits. Two latent classes were identified (low vs. moderate depressive symptoms). Somatic and self-critical symptoms characterized the moderate symptom class. Higher stress overload scores significantly predicted moderate-symptom class membership. DISCUSSION: In this sample of AA women with increased cardiometabolic burden, increased stress was associated with depressive symptoms that standard screening tools may not capture. Research examining the effect of specific stressors and the efficacy of tools to identify at-risk AA women are urgently needed to address disparities and mental health burdens.

Indexed as

Cardiovascular DiseasesDepressionBlack or African AmericanCross-Sectional StudiesFemaleHumansLatent Class AnalysisPhenotypeRetrospective Studies

Identifiers

PMID36729771
PMCPMC9992148
OpenAlexW4318913759

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.