Evidence map›Paper›PMID 36729308›Full record

Trial reportActa diabetologica2023

Compensatory mechanisms from different exercise intensities in type 2 diabetes: a secondary analysis of a 1-year randomized controlled trial.

Inês R Correia, Megan Hetherington-Rauth, João P Magalhães, Pedro B Júdice, Gil B Rosa, Duarte Henriques-Neto, Asier Manas, Ignacio Ara, Analiza M Silva, Luís B Sardinha

2 registry-linked trialsOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Acta diabetologica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03144505 nacompletednot on this map

A 12-Month Randomized Control Trial in Patients With Type 2 Diabetes: Comparing Moderate and High-intensity Interval Training Protocols on Biomarkers and Quality of Life

TypeinterventionalSponsorUniversity of LisbonRan2014 to 2016Enrolled96ConditionsType 2 DiabetesArmsMCT combined with RT Group, HIIT combined with RT Group
NCT07079722 narecruitingnot on this mapstarted 2025, after this paper: background citation

Educational Program for Type 2 Diabetes Prevention With Integrated Physical Exercise: Digital and In-Person Approach

TypeinterventionalSponsorFaculdade de Motricidade HumanaRan2025 to 2026Enrolled90ConditionsPre-diabetesArmsExercise
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Inês R CorreiaFaculdade de Motricidade Humana, Exercise and Health Laboratory, CIPER, Universidade de Lisboa Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Megan Hetherington-RauthFaculdade de Motricidade Humana, Exercise and Health Laboratory, CIPER, Universidade de Lisboa Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
João P MagalhãesFaculdade de Motricidade Humana, Exercise and Health Laboratory, CIPER, Universidade de Lisboa Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Pedro B JúdiceFaculdade de Motricidade Humana, Exercise and Health Laboratory, CIPER, Universidade de Lisboa Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Gil B RosaFaculdade de Motricidade Humana, Exercise and Health Laboratory, CIPER, Universidade de Lisboa Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Duarte Henriques-NetoFaculdade de Motricidade Humana, Exercise and Health Laboratory, CIPER, Universidade de Lisboa Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Asier ManasGENUD Toledo Research Group, University of Castilla-La Mancha, Toledo, Spain.
Ignacio AraGENUD Toledo Research Group, University of Castilla-La Mancha, Toledo, Spain.
Analiza M SilvaFaculdade de Motricidade Humana, Exercise and Health Laboratory, CIPER, Universidade de Lisboa Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Luís B SardinhaFaculdade de Motricidade Humana, Exercise and Health Laboratory, CIPER, Universidade de Lisboa Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal. lsardinha@fmh.ulisboa.pt.ORCID http://orcid.org/0000-0002-6230-6027
University of Lisbon · PTCentro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable · ESUniversity of Castilla-La Mancha · ES

Funding

Fundação para a Ciência e a Tecnologia 2020Fundação para a Ciência e a Tecnologia 2020.07856.BDFundação para a Ciência e a Tecnologia SFRH/BD/149394/2019Fundação para a Ciência e a Tecnologia SFRH/BD/ 85742/2012Fundação para a Ciência e a Tecnologia SFRH/BPD/115977/2016Fundação para a Ciência e a Tecnologia UIDB/00447/2020
6 · The paper itself

Abstract

aimsThis investigation aimed to determine the effect of different intensities of training on non-exercise physical activity (NEPA) and estimated thermogenesis (NEAT) from a 1-year exercise randomized controlled trial (RCT) in individuals with type 2 diabetes mellitus (T2DM) on non-training days. Additionally, changes in NEPA and estimated NEAT in those who failed (low-responders) or succeeded (high-responders) in attaining exercise-derived clinically meaningful reductions in body weight (BW) and fat mass (FM) (i.e., 6% for FM and 3% for BW) was assessed.

methodsIndividuals with T2DM (n = 80) were enrolled in a RCT with three groups: resistance training combined with moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT) and a control group. Of the 80 participants, 56 (completed data) were considered for this secondary analysis. NEPA and estimated NEAT were obtained by accelerometry and body composition through dual-energy X-ray absorptiometry.

resultsAfter adjustments, no time*group interactions were found for estimated NEAT in the MICT (β = - 5.33, p = 0.366) and HIIT (β = - 5.70, p = 0.283), as well as for NEPA in the MICT (β = - 452.83, p = 0.833) and HIIT (β = - 2770.76, p = 0.201), when compared to controls. No compensatory changes in NEPA and estimated NEAT were observed when considering both low-responders and high-responders to FM and BW when compared to controls.

conclusionsBoth MICT and HIIT did not result in any compensatory changes in estimated NEAT and NEPA with the intervention on non-training days. Moreover, no changes in estimated NEAT and NEPA were found when categorizing our participants as low-responders and high-responders to FM and BW when compared to controls. Trial registration clinicaltrials.gov ID. NCT03144505.

Indexed as

Diabetes Mellitus, Type 2Body CompositionBody WeightExerciseHumansCompensationDiabetes mellitusHIITNEATNEPASpontaneous activity

Identifiers

PMID36729308
PMCPMC10063485
OpenAlexW4318934128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.